SOD1-DT

Summary

SOD1-DT (SOD1 divergent transcript, HGNC:55683) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55683
Approved symbol	SOD1-DT
Name	SOD1 divergent transcript
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP000253
Ensembl gene	ENSG00000234509
Ensembl biotype	lncRNA
Entrez	102724449
RNAcentral	URS00026A1FA9 — lncRNA, 2632 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000449339, ENST00000752262

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449339 — 3 exons

Exon	Start	End
ENSE00001553688	31653593	31655427
ENSE00001704984	31659397	31659500
ENSE00001711083	31657934	31658227

Expression profiles

Bgee: expression breadth broad, 97 present calls, max score 80.67.

Top tissues by expression

191 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.67	silver quality
buccal mucosa cell	CL:0002336	67.70	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	67.65	gold quality
sural nerve	UBERON:0015488	63.21	silver quality
liver	UBERON:0002107	60.07	gold quality
stromal cell of endometrium	CL:0002255	59.45	gold quality
ventricular zone	UBERON:0003053	58.87	silver quality
ganglionic eminence	UBERON:0004023	58.24	silver quality
sperm	CL:0000019	58.09	gold quality
right lobe of liver	UBERON:0001114	56.81	gold quality
oviduct epithelium	UBERON:0004804	56.05	silver quality
hindlimb stylopod muscle	UBERON:0004252	55.03	gold quality
adult organism	UBERON:0007023	54.98	silver quality
placenta	UBERON:0001987	54.96	silver quality
endothelial cell	CL:0000115	54.22	gold quality
testis	UBERON:0000473	53.05	gold quality
left testis	UBERON:0004533	51.76	gold quality
right testis	UBERON:0004534	51.76	gold quality
lower lobe of lung	UBERON:0008949	51.39	silver quality
fallopian tube	UBERON:0003889	48.99	silver quality
islet of Langerhans	UBERON:0000006	48.07	gold quality
popliteal artery	UBERON:0002250	47.45	gold quality
tibial artery	UBERON:0007610	47.43	gold quality
prefrontal cortex	UBERON:0000451	47.16	silver quality
monocyte	CL:0000576	47.02	silver quality
blood	UBERON:0000178	46.63	gold quality
aorta	UBERON:0000947	46.60	silver quality
vermiform appendix	UBERON:0001154	46.57	gold quality
muscle of leg	UBERON:0001383	46.51	silver quality
lymph node	UBERON:0000029	46.37	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.09

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Characterization of SOD1-DT, a Divergent Long Non-Coding RNA in the Locus of the SOD1 Human Gene. (PMID:37626868)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.