SOD2-OT1

Summary

SOD2-OT1 (SOD2 overlapping transcript 1, HGNC:53445) is a long non-coding RNA gene on chromosome 6q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53445
Approved symbol	SOD2-OT1
Name	SOD2 overlapping transcript 1
Location	6q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000285427
Ensembl biotype	lncRNA
Entrez	100129518
RNAcentral	URS000075F0E3 — lncRNA, 1718 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000535372

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000535372 — 2 exons

Exon	Start	End
ENSE00002228498	159761994	159762332
ENSE00002284260	159760258	159761636

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 77.17.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.17	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.57	gold quality
adrenal tissue	UBERON:0018303	76.52	gold quality
sural nerve	UBERON:0015488	75.93	gold quality
ganglionic eminence	UBERON:0004023	69.68	gold quality
ventricular zone	UBERON:0003053	68.19	gold quality
bone marrow cell	CL:0002092	66.21	silver quality
cortical plate	UBERON:0005343	65.92	gold quality
prefrontal cortex	UBERON:0000451	64.61	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	62.50	gold quality
liver	UBERON:0002107	61.29	gold quality
frontal cortex	UBERON:0001870	60.77	gold quality
primary visual cortex	UBERON:0002436	60.66	gold quality
right adrenal gland cortex	UBERON:0035827	60.25	gold quality
islet of Langerhans	UBERON:0000006	60.11	gold quality
mucosa of transverse colon	UBERON:0004991	58.82	gold quality
cerebral cortex	UBERON:0000956	58.78	gold quality
right lobe of liver	UBERON:0001114	58.65	gold quality
hypothalamus	UBERON:0001898	58.28	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.19	gold quality
superior frontal gyrus	UBERON:0002661	57.61	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	57.50	gold quality
Brodmann (1909) area 9	UBERON:0013540	57.16	gold quality
substantia nigra	UBERON:0002038	57.05	gold quality
right adrenal gland	UBERON:0001233	56.95	gold quality
anterior cingulate cortex	UBERON:0009835	56.91	gold quality
adrenal gland	UBERON:0002369	56.31	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.24	gold quality
Ammon’s horn	UBERON:0001954	56.16	gold quality
temporal lobe	UBERON:0001871	55.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.02

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.