SORCS3-AS1

Summary

SORCS3-AS1 (SORCS3 antisense RNA 1, HGNC:45244) is a long non-coding RNA gene on chromosome 10q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45244
Approved symbol	SORCS3-AS1
Name	SORCS3 antisense RNA 1
Location	10q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226387
Ensembl biotype	lncRNA
Entrez	100505890
RNAcentral	URS0000759BD2 — lncRNA, 1314 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000449805

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449805 — 2 exons

Exon	Start	End
ENSE00001697920	104664608	104665133
ENSE00004182922	104665449	104666216

Expression profiles

Bgee: expression breadth broad, 44 present calls, max score 98.83.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0302 / max 20.7499, expressed in 4 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
111324	0.0173	3
111323	0.0129	4

Top tissues by expression

177 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	98.83	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.76	gold quality
right testis	UBERON:0004534	88.81	gold quality
left testis	UBERON:0004533	88.72	gold quality
testis	UBERON:0000473	86.08	gold quality
islet of Langerhans	UBERON:0000006	82.83	gold quality
pancreatic ductal cell	CL:0002079	69.01	silver quality
tibialis anterior	UBERON:0001385	68.21	silver quality
mucosa of paranasal sinus	UBERON:0005030	65.64	gold quality
oocyte	CL:0000023	65.01	gold quality
gastrocnemius	UBERON:0001388	62.54	gold quality
epithelium of nasopharynx	UBERON:0001951	62.05	gold quality
deltoid	UBERON:0001476	58.55	gold quality
tibial nerve	UBERON:0001323	58.52	gold quality
adult mammalian kidney	UBERON:0000082	57.11	gold quality
kidney epithelium	UBERON:0004819	56.77	gold quality
superficial temporal artery	UBERON:0001614	56.74	gold quality
cardiac muscle of right atrium	UBERON:0003379	56.13	gold quality
epithelial cell of pancreas	CL:0000083	55.74	gold quality
endothelial cell	CL:0000115	55.34	gold quality
epithelium of mammary gland	UBERON:0003244	54.47	gold quality
mammary duct	UBERON:0001765	54.31	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.02	silver quality
upper arm skin	UBERON:0004263	53.52	gold quality
quadriceps femoris	UBERON:0001377	53.29	gold quality
adult organism	UBERON:0007023	53.28	gold quality
left lobe of thyroid gland	UBERON:0001120	52.63	gold quality
nasal cavity epithelium	UBERON:0005384	52.61	gold quality
sural nerve	UBERON:0015488	52.24	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.