SORL1-AS1

Summary

SORL1-AS1 (SORL1 antisense RNA 1, HGNC:55594) is a long non-coding RNA gene on chromosome 11q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55594
Approved symbol	SORL1-AS1
Name	SORL1 antisense RNA 1
Location	11q24.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	51A
Ensembl gene	ENSG00000246790
Ensembl biotype	lncRNA
Entrez	105369536
RNAcentral	URS00026A1B6D — lncRNA, 1981 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000501964, ENST00000529160, ENST00000715254, ENST00000715255, ENST00000816477, ENST00000816478, ENST00000816479

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501964 — 2 exons

Exon	Start	End
ENSE00001960913	121447331	121449899
ENSE00001972032	121452675	121453013

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 68.95.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	68.95	silver quality
colonic epithelium	UBERON:0000397	67.74	silver quality
cortical plate	UBERON:0005343	67.25	gold quality
blood	UBERON:0000178	67.23	gold quality
bone marrow	UBERON:0002371	65.88	gold quality
lymph node	UBERON:0000029	63.61	gold quality
granulocyte	CL:0000094	61.81	gold quality
leukocyte	CL:0000738	58.38	gold quality
prefrontal cortex	UBERON:0000451	58.37	gold quality
tonsil	UBERON:0002372	58.17	gold quality
descending thoracic aorta	UBERON:0002345	57.87	gold quality
duodenum	UBERON:0002114	56.96	gold quality
islet of Langerhans	UBERON:0000006	56.83	gold quality
monocyte	CL:0000576	56.73	gold quality
vermiform appendix	UBERON:0001154	56.53	gold quality
liver	UBERON:0002107	55.38	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.22	gold quality
pancreas	UBERON:0001264	54.23	gold quality
muscle of leg	UBERON:0001383	52.49	gold quality
primary visual cortex	UBERON:0002436	52.23	gold quality
calcaneal tendon	UBERON:0003701	51.73	silver quality
rectum	UBERON:0001052	51.38	gold quality
uterine cervix	UBERON:0000002	51.31	gold quality
multicellular organism	UBERON:0000468	51.04	gold quality
lower esophagus mucosa	UBERON:0035834	50.77	gold quality
urinary bladder	UBERON:0001255	50.60	gold quality
corpus callosum	UBERON:0002336	50.29	gold quality
frontal cortex	UBERON:0001870	49.98	gold quality
superior frontal gyrus	UBERON:0002661	49.98	gold quality
right lobe of liver	UBERON:0001114	49.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.