SOX5-AS1

Summary

SOX5-AS1 (SOX5 antisense RNA 1, HGNC:53311) is a long non-coding RNA gene on chromosome 12p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53311
Approved symbol	SOX5-AS1
Name	SOX5 antisense RNA 1
Location	12p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256120
Ensembl biotype	lncRNA
Entrez	101928471
RNAcentral	URS000075D50E — lncRNA, 589 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000539583, ENST00000540733, ENST00000654390, ENST00000655279, ENST00000656072, ENST00000657983, ENST00000659871, ENST00000660859, ENST00000661840, ENST00000662250, ENST00000662701, ENST00000665769, ENST00000665959, ENST00000666329, ENST00000668226, ENST00000668312, ENST00000668875, ENST00000670751, ENST00000810679, ENST00000810680, ENST00000810681, ENST00000810682

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000539583 — 7 exons

Exon	Start	End
ENSE00002239555	24227161	24227387
ENSE00002256958	24230559	24230615
ENSE00002273617	24237822	24238043
ENSE00002305946	24227711	24227818
ENSE00003884401	24239451	24239567
ENSE00003885264	24223240	24223323
ENSE00004207853	24254852	24255103

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 89.71.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0132 / max 7.2174, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
124716	0.0132	3

Top tissues by expression

103 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.71	gold quality
calcaneal tendon	UBERON:0003701	82.84	gold quality
left testis	UBERON:0004533	82.58	gold quality
testis	UBERON:0000473	81.98	gold quality
right testis	UBERON:0004534	80.49	gold quality
liver	UBERON:0002107	69.80	gold quality
cortical plate	UBERON:0005343	68.89	gold quality
bone marrow	UBERON:0002371	67.57	silver quality
bone marrow cell	CL:0002092	67.12	silver quality
colonic epithelium	UBERON:0000397	66.94	silver quality
thymus	UBERON:0002370	66.85	silver quality
tonsil	UBERON:0002372	65.66	gold quality
skeletal muscle tissue	UBERON:0001134	65.34	silver quality
lung	UBERON:0002048	63.74	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
corpus callosum	UBERON:0002336	60.87	gold quality
myometrium	UBERON:0001296	59.87	gold quality
ganglionic eminence	UBERON:0004023	58.65	gold quality
urinary bladder	UBERON:0001255	58.51	silver quality
uterine cervix	UBERON:0000002	57.97	silver quality
adrenal tissue	UBERON:0018303	57.51	gold quality
adrenal gland	UBERON:0002369	56.55	gold quality
stomach	UBERON:0000945	55.85	gold quality
kidney	UBERON:0002113	55.00	gold quality
multicellular organism	UBERON:0000468	54.80	gold quality
endometrium	UBERON:0001295	54.14	silver quality
blood	UBERON:0000178	53.87	gold quality
adult mammalian kidney	UBERON:0000082	53.37	gold quality
monocyte	CL:0000576	53.21	gold quality
right lobe of liver	UBERON:0001114	51.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.88

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.