SP2-AS1

Summary

SP2-AS1 (SP2 antisense RNA 1, HGNC:51341) is a long non-coding RNA gene on chromosome 17q21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51341
Approved symbol	SP2-AS1
Name	SP2 antisense RNA 1
Location	17q21.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234494
Ensembl biotype	lncRNA
Entrez	100506325
RNAcentral	URS000075EE8D — lncRNA, 2182 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 29 — 29 lncRNA

ENST00000411573, ENST00000433001, ENST00000451140, ENST00000577279, ENST00000580459, ENST00000582787, ENST00000584276, ENST00000585280, ENST00000691236, ENST00000702616, ENST00000715779, ENST00000820515, ENST00000820516, ENST00000820517, ENST00000820518, ENST00000820519, ENST00000820520, ENST00000820521, ENST00000820522, ENST00000820523, ENST00000820524, ENST00000820525, ENST00000820526, ENST00000820527, ENST00000820528, ENST00000820529, ENST00000820530, ENST00000820531, ENST00000820532

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411573 — 3 exons

Exon	Start	End
ENSE00001664996	47918452	47918571
ENSE00001682257	47898713	47900378
ENSE00001740266	47941336	47941392

Expression profiles

Bgee: expression breadth ubiquitous, 167 present calls, max score 85.73.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1198 / max 54.2742, expressed in 686 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
166616	3.2785	1462
166617	1.1198	686

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreatic ductal cell	CL:0002079	85.73	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.58	gold quality
buccal mucosa cell	CL:0002336	82.66	gold quality
smooth muscle tissue	UBERON:0001135	75.27	gold quality
calcaneal tendon	UBERON:0003701	75.10	gold quality
cortical plate	UBERON:0005343	75.03	gold quality
bone marrow cell	CL:0002092	73.37	silver quality
right coronary artery	UBERON:0001625	72.99	gold quality
islet of Langerhans	UBERON:0000006	72.96	gold quality
sural nerve	UBERON:0015488	72.23	gold quality
stromal cell of endometrium	CL:0002255	71.85	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.54	gold quality
left uterine tube	UBERON:0001303	71.19	gold quality
right lobe of thyroid gland	UBERON:0001119	71.18	gold quality
prefrontal cortex	UBERON:0000451	71.09	gold quality
left coronary artery	UBERON:0001626	70.87	gold quality
left lobe of thyroid gland	UBERON:0001120	70.27	gold quality
thyroid gland	UBERON:0002046	70.11	gold quality
coronary artery	UBERON:0001621	69.71	gold quality
mucosa of stomach	UBERON:0001199	69.68	gold quality
monocyte	CL:0000576	69.66	gold quality
anterior cingulate cortex	UBERON:0009835	69.63	gold quality
leukocyte	CL:0000738	69.45	gold quality
rectum	UBERON:0001052	69.42	gold quality
granulocyte	CL:0000094	69.39	gold quality
tibial nerve	UBERON:0001323	69.39	gold quality
right frontal lobe	UBERON:0002810	69.21	gold quality
left ovary	UBERON:0002119	69.11	gold quality
omental fat pad	UBERON:0010414	69.10	gold quality
peritoneum	UBERON:0002358	69.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.