SPANXA2-OT1

Summary

SPANXA2-OT1 (SPANXA2 overlapping transcript 1, HGNC:31683) is a long non-coding RNA gene on chromosome Xq27.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31683
Approved symbol	SPANXA2-OT1
Name	SPANXA2 overlapping transcript 1
Location	Xq27.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ36186
Ensembl gene	ENSG00000277215
Ensembl biotype	lncRNA
Entrez	619455
RNAcentral	URS000075B855 — lncRNA, 1698 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000622372, ENST00000662492, ENST00000664367, ENST00000665569, ENST00000666172, ENST00000666501, ENST00000781068, ENST00000786809

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000622372 — 4 exons

Exon	Start	End
ENSE00001655585	141514712	141514829
ENSE00003731644	141502849	141503239
ENSE00003734041	141520472	141520519
ENSE00003735024	141648799	141649927

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 86.49.

Top tissues by expression

220 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.49	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.17	gold quality
colonic epithelium	UBERON:0000397	71.42	silver quality
descending thoracic aorta	UBERON:0002345	66.01	gold quality
thoracic aorta	UBERON:0001515	63.50	gold quality
cortical plate	UBERON:0005343	63.40	gold quality
ascending aorta	UBERON:0001496	63.29	gold quality
ganglionic eminence	UBERON:0004023	62.40	gold quality
aorta	UBERON:0000947	61.22	gold quality
ventricular zone	UBERON:0003053	61.12	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	60.77	gold quality
popliteal artery	UBERON:0002250	59.73	gold quality
tibial artery	UBERON:0007610	59.66	gold quality
sural nerve	UBERON:0015488	59.14	silver quality
spinal cord	UBERON:0002240	59.02	gold quality
right coronary artery	UBERON:0001625	58.93	gold quality
left coronary artery	UBERON:0001626	57.89	gold quality
stromal cell of endometrium	CL:0002255	57.31	gold quality
coronary artery	UBERON:0001621	56.93	gold quality
prefrontal cortex	UBERON:0000451	54.88	gold quality
substantia nigra	UBERON:0002038	53.72	gold quality
monocyte	CL:0000576	52.52	silver quality
midbrain	UBERON:0001891	52.17	gold quality
lower lobe of lung	UBERON:0008949	51.91	silver quality
right uterine tube	UBERON:0001302	50.70	gold quality
corpus callosum	UBERON:0002336	50.65	silver quality
hypothalamus	UBERON:0001898	50.64	gold quality
islet of Langerhans	UBERON:0000006	50.32	gold quality
amygdala	UBERON:0001876	49.87	gold quality
right lobe of liver	UBERON:0001114	49.71	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.