SPATA42

Summary

SPATA42 (spermatogenesis associated 42, HGNC:41198) is a long non-coding RNA gene on chromosome 1p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41198
Approved symbol	SPATA42
Name	spermatogenesis associated 42
Location	1p13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	SRG7, AKNAD1-AS1
Ensembl gene	ENSG00000203897
Ensembl biotype	lncRNA
Entrez	642864
RNAcentral	URS000075BBB0 — lncRNA, 546 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000369989, ENST00000417241, ENST00000662170, ENST00000755133, ENST00000755134

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000369989 — 3 exons

Exon	Start	End
ENSE00001451428	108858158	108858267
ENSE00004103825	108857165	108857501
ENSE00004103826	108858385	108858529

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 99.08.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0562 / max 60.8965, expressed in 5 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4368	0.0290	5
4369	0.0115	4
4371	0.0083	3
4370	0.0073	3

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	99.08	gold quality
left testis	UBERON:0004533	98.78	gold quality
right testis	UBERON:0004534	98.10	gold quality
testis	UBERON:0000473	95.77	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.56	gold quality
adult organism	UBERON:0007023	82.80	gold quality
sural nerve	UBERON:0015488	75.44	gold quality
ganglionic eminence	UBERON:0004023	66.00	gold quality
pancreatic ductal cell	CL:0002079	64.67	silver quality
cauda epididymis	UBERON:0004360	57.23	gold quality
monocyte	CL:0000576	55.89	gold quality
prefrontal cortex	UBERON:0000451	55.51	gold quality
muscle of leg	UBERON:0001383	55.44	gold quality
stromal cell of endometrium	CL:0002255	55.41	gold quality
gastrocnemius	UBERON:0001388	55.37	gold quality
epithelial cell of pancreas	CL:0000083	55.22	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.20	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
islet of Langerhans	UBERON:0000006	54.29	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
skin of abdomen	UBERON:0001416	53.04	gold quality
hypothalamus	UBERON:0001898	51.67	gold quality
tibialis anterior	UBERON:0001385	51.40	silver quality
buccal mucosa cell	CL:0002336	51.10	gold quality
skin of leg	UBERON:0001511	50.71	gold quality
myocardium	UBERON:0002349	50.25	gold quality
zone of skin	UBERON:0000014	50.21	gold quality
right adrenal gland cortex	UBERON:0035827	50.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.