SPCS3-AS1

Summary

SPCS3-AS1 (SPCS3 antisense RNA 1, HGNC:54818) is a long non-coding RNA gene on chromosome 4q34.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54818
Approved symbol	SPCS3-AS1
Name	SPCS3 antisense RNA 1
Location	4q34.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248980
Ensembl biotype	lncRNA
Entrez	116435303
RNAcentral	URS00026A20E7 — lncRNA, 672 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000512634

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000512634 — 3 exons

Exon	Start	End
ENSE00002025875	176308268	176308467
ENSE00002030863	176320145	176320458
ENSE00002043330	176311488	176311583

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 96.14.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
urinary bladder	UBERON:0001255	96.14	gold quality
sural nerve	UBERON:0015488	80.06	gold quality
skeletal muscle tissue	UBERON:0001134	76.02	silver quality
ganglionic eminence	UBERON:0004023	60.91	gold quality
ventricular zone	UBERON:0003053	60.88	gold quality
adult mammalian kidney	UBERON:0000082	59.54	gold quality
stromal cell of endometrium	CL:0002255	59.33	gold quality
kidney	UBERON:0002113	58.72	gold quality
blood	UBERON:0000178	55.11	gold quality
endometrium	UBERON:0001295	53.98	gold quality
leukocyte	CL:0000738	53.57	silver quality
granulocyte	CL:0000094	53.42	gold quality
liver	UBERON:0002107	53.15	gold quality
monocyte	CL:0000576	52.80	silver quality
prefrontal cortex	UBERON:0000451	52.37	gold quality
placenta	UBERON:0001987	52.36	gold quality
islet of Langerhans	UBERON:0000006	51.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	51.90	gold quality
bone marrow	UBERON:0002371	50.86	silver quality
gall bladder	UBERON:0002110	50.73	gold quality
primary visual cortex	UBERON:0002436	49.76	gold quality
pancreas	UBERON:0001264	49.63	gold quality
right lobe of liver	UBERON:0001114	49.45	silver quality
lymph node	UBERON:0000029	48.14	silver quality
muscle of leg	UBERON:0001383	47.91	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	47.85	gold quality
gastrocnemius	UBERON:0001388	47.45	gold quality
saliva-secreting gland	UBERON:0001044	47.22	gold quality
cerebellum	UBERON:0002037	47.20	gold quality
frontal cortex	UBERON:0001870	47.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.83

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.