SPDYE1-AS1

Summary

SPDYE1-AS1 (SPDYE1 and UBE2D4 antisense RNA 1, HGNC:56874) is a long non-coding RNA gene on chromosome 7p13.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56874
Approved symbol	SPDYE1-AS1
Name	SPDYE1 and UBE2D4 antisense RNA 1
Location	7p13
Locus type	RNA, long non-coding
Status	Approved
Aliases	RASA4CP-POLR2J4-UPK3BL3P-RASA4EP
Ensembl gene	ENSG00000214783
Entrez	131554431

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Bgee: expression breadth ubiquitous, 168 present calls, max score 82.89.

Top tissues by expression

252 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cardiac muscle of right atrium	UBERON:0003379	82.89	gold quality
kidney epithelium	UBERON:0004819	82.12	gold quality
left ventricle myocardium	UBERON:0006566	81.50	gold quality
cortical plate	UBERON:0005343	77.77	gold quality
ventricular zone	UBERON:0003053	77.53	gold quality
ganglionic eminence	UBERON:0004023	77.51	gold quality
prefrontal cortex	UBERON:0000451	77.20	gold quality
upper arm skin	UBERON:0004263	76.91	gold quality
nasal cavity epithelium	UBERON:0005384	76.60	gold quality
stromal cell of endometrium	CL:0002255	76.43	gold quality
cerebellar cortex	UBERON:0002129	75.85	gold quality
right hemisphere of cerebellum	UBERON:0014890	75.81	gold quality
cerebellar hemisphere	UBERON:0002245	75.78	gold quality
sural nerve	UBERON:0015488	75.76	gold quality
vagina	UBERON:0000996	75.66	gold quality
esophagus mucosa	UBERON:0002469	75.57	gold quality
epithelial cell of pancreas	CL:0000083	75.56	gold quality
granulocyte	CL:0000094	75.17	gold quality
colonic epithelium	UBERON:0000397	75.13	gold quality
cerebellum	UBERON:0002037	75.12	gold quality
ectocervix	UBERON:0012249	75.07	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.91	gold quality
left ovary	UBERON:0002119	74.89	gold quality
right ovary	UBERON:0002118	74.50	gold quality
esophagus	UBERON:0001043	74.34	gold quality
right frontal lobe	UBERON:0002810	74.25	gold quality
tibial artery	UBERON:0007610	73.93	gold quality
popliteal artery	UBERON:0002250	73.92	gold quality
lower esophagus mucosa	UBERON:0035834	73.67	gold quality
body of uterus	UBERON:0009853	73.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.