SPECC1-DT

Summary

SPECC1-DT (SPECC1 divergent transcript, HGNC:55376) is a long non-coding RNA gene on chromosome 17p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55376
Approved symbol	SPECC1-DT
Name	SPECC1 divergent transcript
Location	17p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261033
Ensembl biotype	lncRNA
Entrez	119545627
RNAcentral	URS00026A279C — lncRNA, 1206 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000564549

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000564549 — 1 exons

Exon	Start	End
ENSE00002587650	20008051	20009234

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 84.48.

Top tissues by expression

205 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.48	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.49	gold quality
oocyte	CL:0000023	74.87	gold quality
prefrontal cortex	UBERON:0000451	70.74	gold quality
medial globus pallidus	UBERON:0002477	70.10	gold quality
Brodmann (1909) area 23	UBERON:0013554	68.65	silver quality
primary visual cortex	UBERON:0002436	66.81	gold quality
globus pallidus	UBERON:0001875	66.74	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.68	gold quality
frontal cortex	UBERON:0001870	66.62	gold quality
neocortex	UBERON:0001950	66.25	gold quality
cardia of stomach	UBERON:0001162	66.06	gold quality
anterior cingulate cortex	UBERON:0009835	65.87	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	65.77	gold quality
right frontal lobe	UBERON:0002810	65.55	gold quality
nasal cavity epithelium	UBERON:0005384	65.11	gold quality
parotid gland	UBERON:0001831	64.74	gold quality
cerebellar vermis	UBERON:0004720	64.69	silver quality
cerebral cortex	UBERON:0000956	64.22	gold quality
pons	UBERON:0000988	63.94	gold quality
tendon of biceps brachii	UBERON:0008188	63.91	gold quality
occipital lobe	UBERON:0002021	63.63	gold quality
substantia nigra	UBERON:0002038	62.20	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	61.91	gold quality
hypothalamus	UBERON:0001898	61.75	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	61.61	gold quality
midbrain	UBERON:0001891	61.18	gold quality
endothelial cell	CL:0000115	61.11	silver quality
forebrain	UBERON:0001890	60.94	gold quality
ventricular zone	UBERON:0003053	60.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.