SPTBN1-AS1

Summary

SPTBN1-AS1 (SPTBN1 antisense RNA 1, HGNC:40562) is a long non-coding RNA gene on chromosome 2p16.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40562
Approved symbol	SPTBN1-AS1
Name	SPTBN1 antisense RNA 1
Location	2p16.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228108
Ensembl biotype	lncRNA
Entrez	105374640
RNAcentral	URS00026A1B45 — lncRNA, 2353 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000433475

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433475 — 4 exons

Exon	Start	End
ENSE00001703077	54540599	54540697
ENSE00001717110	54520330	54520465
ENSE00001736843	54535040	54535138
ENSE00001747951	54516048	54516249

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 86.58.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.58	silver quality
corpus callosum	UBERON:0002336	71.64	gold quality
skeletal muscle tissue	UBERON:0001134	71.31	gold quality
urinary bladder	UBERON:0001255	66.06	silver quality
gall bladder	UBERON:0002110	64.51	gold quality
sural nerve	UBERON:0015488	64.26	silver quality
hindlimb stylopod muscle	UBERON:0004252	64.08	gold quality
ganglionic eminence	UBERON:0004023	63.61	gold quality
adrenal tissue	UBERON:0018303	62.73	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.95	gold quality
calcaneal tendon	UBERON:0003701	61.51	gold quality
tonsil	UBERON:0002372	60.32	silver quality
liver	UBERON:0002107	57.76	gold quality
lung	UBERON:0002048	56.28	gold quality
placenta	UBERON:0001987	56.19	gold quality
duodenum	UBERON:0002114	55.96	gold quality
islet of Langerhans	UBERON:0000006	55.09	gold quality
vermiform appendix	UBERON:0001154	54.21	gold quality
myometrium	UBERON:0001296	53.82	gold quality
kidney	UBERON:0002113	53.76	gold quality
muscle of leg	UBERON:0001383	53.14	gold quality
monocyte	CL:0000576	52.56	gold quality
pancreas	UBERON:0001264	51.58	gold quality
right lobe of liver	UBERON:0001114	50.54	silver quality
gastrocnemius	UBERON:0001388	50.52	gold quality
testis	UBERON:0000473	50.45	gold quality
left testis	UBERON:0004533	50.31	gold quality
stomach	UBERON:0000945	50.18	gold quality
prefrontal cortex	UBERON:0000451	50.15	gold quality
blood	UBERON:0000178	49.14	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.