SPTBN1-AS2

Summary

SPTBN1-AS2 (SPTBN1 antisense RNA 2, HGNC:40563) is a long non-coding RNA gene on chromosome 2p16.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40563
Approved symbol	SPTBN1-AS2
Name	SPTBN1 antisense RNA 2
Location	2p16.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000238018
Ensembl biotype	lncRNA
Entrez	123706536
RNAcentral	URS00026A211C — lncRNA, 743 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000456363, ENST00000626206

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456363 — 2 exons

Exon	Start	End
ENSE00001659052	54661011	54661375
ENSE00001697950	54662556	54662792

Expression profiles

Bgee: expression breadth ubiquitous, 170 present calls, max score 97.35.

Top tissues by expression

294 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tibial nerve	UBERON:0001323	97.35	gold quality
right lung	UBERON:0002167	95.23	gold quality
colonic epithelium	UBERON:0000397	94.38	gold quality
upper lobe of left lung	UBERON:0008952	94.32	gold quality
apex of heart	UBERON:0002098	92.94	gold quality
upper lobe of lung	UBERON:0008948	91.66	gold quality
right atrium auricular region	UBERON:0006631	91.35	gold quality
heart left ventricle	UBERON:0002084	90.87	gold quality
lower esophagus muscularis layer	UBERON:0035833	90.86	gold quality
lower esophagus	UBERON:0013473	90.78	gold quality
mucosa of stomach	UBERON:0001199	90.47	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	90.36	gold quality
cardiac ventricle	UBERON:0002082	89.89	gold quality
omental fat pad	UBERON:0010414	89.89	gold quality
peritoneum	UBERON:0002358	89.76	gold quality
muscle layer of sigmoid colon	UBERON:0035805	89.72	gold quality
right coronary artery	UBERON:0001625	89.26	gold quality
tendon	UBERON:0000043	89.14	gold quality
calcaneal tendon	UBERON:0003701	89.13	gold quality
right adrenal gland cortex	UBERON:0035827	89.11	gold quality
left ovary	UBERON:0002119	89.10	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.07	gold quality
adipose tissue of abdominal region	UBERON:0007808	88.70	gold quality
right ovary	UBERON:0002118	88.48	gold quality
tendon of biceps brachii	UBERON:0008188	88.47	silver quality
body of uterus	UBERON:0009853	88.30	gold quality
left coronary artery	UBERON:0001626	88.21	gold quality
cardiac atrium	UBERON:0002081	87.98	gold quality
heart	UBERON:0000948	87.84	gold quality
metanephros cortex	UBERON:0010533	87.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.