SRD5A3-AS1

Summary

SRD5A3-AS1 (SRD5A3 antisense RNA 1, HGNC:44138) is a long non-coding RNA gene on chromosome 4q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44138
Approved symbol	SRD5A3-AS1
Name	SRD5A3 antisense RNA 1
Location	4q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249700
Ensembl biotype	lncRNA
Entrez	100506462
RNAcentral	URS000075B6E1 — lncRNA, 943 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 31 lncRNA, 4 retained_intron

ENST00000433175, ENST00000510637, ENST00000591915, ENST00000592823, ENST00000595103, ENST00000595734, ENST00000596289, ENST00000596312, ENST00000598819, ENST00000598906, ENST00000599135, ENST00000601433, ENST00000608086, ENST00000608136, ENST00000608265, ENST00000608558, ENST00000609051, ENST00000609487, ENST00000609500, ENST00000609573, ENST00000609580, ENST00000609700, ENST00000610396, ENST00000613794, ENST00000619203, ENST00000619685, ENST00000619912, ENST00000666009, ENST00000819835, ENST00000819836, ENST00000819837, ENST00000819838, ENST00000819839, ENST00000819840, ENST00000819841

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433175 — 5 exons

Exon	Start	End
ENSE00001749341	55383292	55383396
ENSE00002021949	55366756	55367163
ENSE00002037413	55365608	55365661
ENSE00002054387	55363971	55364857
ENSE00002061561	55374871	55375033

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 86.68.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0175 / max 17.5923, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
52158	0.0175	3

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	86.68	gold quality
left testis	UBERON:0004533	86.67	gold quality
right testis	UBERON:0004534	86.66	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.54	gold quality
testis	UBERON:0000473	83.43	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	81.83	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.67	gold quality
spinal cord	UBERON:0002240	78.09	gold quality
tibial nerve	UBERON:0001323	76.83	gold quality
sural nerve	UBERON:0015488	76.63	gold quality
cortical plate	UBERON:0005343	76.55	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.15	gold quality
putamen	UBERON:0001874	76.03	gold quality
amygdala	UBERON:0001876	75.48	gold quality
monocyte	CL:0000576	75.18	gold quality
right frontal lobe	UBERON:0002810	74.83	gold quality
leukocyte	CL:0000738	74.37	gold quality
anterior cingulate cortex	UBERON:0009835	74.33	gold quality
caudate nucleus	UBERON:0001873	73.79	gold quality
nucleus accumbens	UBERON:0001882	73.66	gold quality
gastrocnemius	UBERON:0001388	73.65	gold quality
gall bladder	UBERON:0002110	73.59	gold quality
prefrontal cortex	UBERON:0000451	73.56	gold quality
muscle of leg	UBERON:0001383	73.54	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.28	gold quality
thoracic aorta	UBERON:0001515	73.13	gold quality
ascending aorta	UBERON:0001496	73.11	gold quality
descending thoracic aorta	UBERON:0002345	72.75	gold quality
tibial artery	UBERON:0007610	72.71	gold quality
hypothalamus	UBERON:0001898	72.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.