SRGAP3-AS2

Summary

SRGAP3-AS2 (SRGAP3 antisense RNA 2, HGNC:40899) is a long non-coding RNA gene on chromosome 3p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40899
Approved symbol	SRGAP3-AS2
Name	SRGAP3 antisense RNA 2
Location	3p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228723
Ensembl biotype	lncRNA
Entrez	101927416
RNAcentral	URS000075C763 — lncRNA, 1310 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000436032, ENST00000450920, ENST00000600323, ENST00000612302, ENST00000614304

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436032 — 3 exons

Exon	Start	End
ENSE00001595000	9193429	9193490
ENSE00001605141	9192493	9192995
ENSE00004276593	9193726	9194453

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 98.52.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0504 / max 25.1158, expressed in 14 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
35198	0.0359	13
35200	0.0112	5
35199	0.0032	2

Top tissues by expression

205 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bronchial epithelial cell	CL:0002328	98.52	gold quality
bronchus	UBERON:0002185	96.77	gold quality
mucosa of paranasal sinus	UBERON:0005030	89.93	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	89.40	gold quality
right uterine tube	UBERON:0001302	89.16	gold quality
epithelium of nasopharynx	UBERON:0001951	81.51	gold quality
endocervix	UBERON:0000458	77.08	gold quality
right lung	UBERON:0002167	75.03	gold quality
bone marrow cell	CL:0002092	74.16	gold quality
fallopian tube	UBERON:0003889	73.07	gold quality
oviduct epithelium	UBERON:0004804	72.37	gold quality
endothelial cell	CL:0000115	68.07	gold quality
adrenal tissue	UBERON:0018303	67.62	gold quality
nasal cavity mucosa	UBERON:0001826	65.52	gold quality
upper lobe of left lung	UBERON:0008952	63.65	gold quality
upper lobe of lung	UBERON:0008948	61.97	gold quality
lung	UBERON:0002048	61.42	gold quality
sural nerve	UBERON:0015488	60.76	gold quality
right adrenal gland cortex	UBERON:0035827	59.36	gold quality
left uterine tube	UBERON:0001303	59.13	gold quality
corpus callosum	UBERON:0002336	57.85	gold quality
uterine cervix	UBERON:0000002	56.52	gold quality
trachea	UBERON:0003126	56.51	silver quality
adrenal gland	UBERON:0002369	56.28	gold quality
left adrenal gland	UBERON:0001234	55.56	gold quality
right adrenal gland	UBERON:0001233	55.39	gold quality
cerebellar vermis	UBERON:0004720	55.34	gold quality
calcaneal tendon	UBERON:0003701	54.84	gold quality
adrenal cortex	UBERON:0001235	53.48	gold quality
tonsil	UBERON:0002372	53.45	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.