SRGAP3-AS4

Summary

SRGAP3-AS4 (SRGAP3 antisense RNA 4, HGNC:42434) is a long non-coding RNA gene on chromosome 3p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42434
Approved symbol	SRGAP3-AS4
Name	SRGAP3 antisense RNA 4
Location	3p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235830
Ensembl biotype	lncRNA
Entrez	101927440
RNAcentral	URS0000BC448F — lncRNA, 443 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000449023, ENST00000762419, ENST00000762420, ENST00000762421, ENST00000762422, ENST00000762423

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000449023 — 3 exons

Exon	Start	End
ENSE00001601324	9256759	9257000
ENSE00004117540	9257373	9257508
ENSE00004117550	9249716	9249821

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 74.28.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
heart left ventricle	UBERON:0002084	74.28	gold quality
bone marrow cell	CL:0002092	72.53	gold quality
apex of heart	UBERON:0002098	71.19	gold quality
right uterine tube	UBERON:0001302	68.86	gold quality
ganglionic eminence	UBERON:0004023	68.77	gold quality
ventricular zone	UBERON:0003053	68.68	gold quality
heart	UBERON:0000948	67.17	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.59	gold quality
fallopian tube	UBERON:0003889	64.54	gold quality
skeletal muscle tissue	UBERON:0001134	64.53	gold quality
placenta	UBERON:0001987	63.43	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.66	gold quality
prefrontal cortex	UBERON:0000451	59.79	gold quality
islet of Langerhans	UBERON:0000006	59.53	gold quality
muscle of leg	UBERON:0001383	59.52	gold quality
tonsil	UBERON:0002372	59.29	silver quality
right adrenal gland cortex	UBERON:0035827	58.12	gold quality
gastrocnemius	UBERON:0001388	58.05	gold quality
gall bladder	UBERON:0002110	58.03	gold quality
corpus callosum	UBERON:0002336	57.54	gold quality
endometrium	UBERON:0001295	57.02	gold quality
superior frontal gyrus	UBERON:0002661	56.98	gold quality
lymph node	UBERON:0000029	56.78	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	56.59	gold quality
duodenum	UBERON:0002114	56.42	gold quality
right atrium auricular region	UBERON:0006631	56.05	gold quality
right adrenal gland	UBERON:0001233	55.53	gold quality
saliva-secreting gland	UBERON:0001044	55.52	gold quality
substantia nigra	UBERON:0002038	54.81	gold quality
adrenal gland	UBERON:0002369	54.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.01

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.