SRP14-DT

Summary

SRP14-DT (SRP14 divergent transcript, HGNC:48619) is a long non-coding RNA gene on chromosome 15q15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48619
Approved symbol	SRP14-DT
Name	SRP14 divergent transcript
Location	15q15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248508
Ensembl biotype	lncRNA
Entrez	100131089
RNAcentral	URS000075A00B — lncRNA, 2819 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 35 lncRNA

ENST00000504245, ENST00000559012, ENST00000560341, ENST00000616620, ENST00000655221, ENST00000660446, ENST00000661955, ENST00000667323, ENST00000668306, ENST00000692845, ENST00000702074, ENST00000746676, ENST00000746677, ENST00000746678, ENST00000746679, ENST00000746680, ENST00000746681, ENST00000746682, ENST00000746683, ENST00000746684, ENST00000746685, ENST00000746686, ENST00000746687, ENST00000746688, ENST00000746689, ENST00000746690, ENST00000746691, ENST00000746692, ENST00000746693, ENST00000746694, ENST00000746695, ENST00000746696, ENST00000746697, ENST00000746698, ENST00000746699

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504245 — 3 exons

Exon	Start	End
ENSE00002059000	40045961	40046069
ENSE00004087865	40065221	40067496
ENSE00004087886	40039248	40039448

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 92.52.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.3756 / max 41.4549, expressed in 1648 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
146065	4.3756	1648

Top tissues by expression

137 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	92.52	gold quality
spinal cord	UBERON:0002240	92.49	gold quality
cerebellar vermis	UBERON:0004720	91.07	gold quality
substantia nigra	UBERON:0002038	89.77	gold quality
apex of heart	UBERON:0002098	88.77	gold quality
right uterine tube	UBERON:0001302	88.57	gold quality
heart left ventricle	UBERON:0002084	87.61	gold quality
amygdala	UBERON:0001876	87.44	gold quality
temporal lobe	UBERON:0001871	87.26	gold quality
thymus	UBERON:0002370	87.11	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.91	gold quality
Ammon’s horn	UBERON:0001954	86.86	gold quality
hypothalamus	UBERON:0001898	86.53	gold quality
putamen	UBERON:0001874	86.43	gold quality
hindlimb stylopod muscle	UBERON:0004252	86.36	gold quality
caudate nucleus	UBERON:0001873	85.60	gold quality
nucleus accumbens	UBERON:0001882	84.56	gold quality
heart	UBERON:0000948	84.54	gold quality
corpus callosum	UBERON:0002336	83.89	gold quality
islet of Langerhans	UBERON:0000006	83.65	gold quality
right atrium auricular region	UBERON:0006631	83.62	gold quality
skeletal muscle tissue	UBERON:0001134	83.18	gold quality
right adrenal gland cortex	UBERON:0035827	82.60	gold quality
muscle of leg	UBERON:0001383	82.56	gold quality
right adrenal gland	UBERON:0001233	82.53	gold quality
gastrocnemius	UBERON:0001388	82.43	gold quality
right lobe of thyroid gland	UBERON:0001119	82.21	gold quality
thyroid gland	UBERON:0002046	82.13	gold quality
pituitary gland	UBERON:0000007	81.79	gold quality
left lobe of thyroid gland	UBERON:0001120	81.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.