SRP54-AS1

Summary

SRP54-AS1 (SRP54 antisense RNA 1, HGNC:50643) is a long non-coding RNA gene on chromosome 14q13.2.

At a glance

• Gene type: non-coding (transcribed_unitary_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50643
Approved symbol	SRP54-AS1
Name	SRP54 antisense RNA 1
Location	14q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258704
Ensembl biotype	transcribed_unitary_pseudogene
Entrez	100506157
RNAcentral	URS0000CCE0AE — lncRNA, 1062 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unitary_pseudogene

ENST00000636540

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000636540 — 5 exons

Exon	Start	End
ENSE00002491120	34963929	34964040
ENSE00002522038	34954859	34954954
ENSE00002527928	34969170	34969307
ENSE00003795136	34982430	34982526
ENSE00003795598	34965561	34965682

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 87.72.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.7208 / max 91.3627, expressed in 1739 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
142832	3.5186	1361
142831	2.0813	832
142833	1.2358	649
142834	0.8851	514

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.72	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.91	gold quality
blood	UBERON:0000178	76.53	gold quality
corpus callosum	UBERON:0002336	76.16	gold quality
right lobe of liver	UBERON:0001114	74.52	gold quality
calcaneal tendon	UBERON:0003701	74.08	gold quality
descending thoracic aorta	UBERON:0002345	73.91	gold quality
adult mammalian kidney	UBERON:0000082	73.86	gold quality
sural nerve	UBERON:0015488	72.65	gold quality
right uterine tube	UBERON:0001302	72.24	gold quality
lymph node	UBERON:0000029	72.11	gold quality
liver	UBERON:0002107	72.01	gold quality
stromal cell of endometrium	CL:0002255	71.39	gold quality
granulocyte	CL:0000094	71.18	gold quality
kidney	UBERON:0002113	71.17	gold quality
thoracic aorta	UBERON:0001515	71.12	gold quality
ascending aorta	UBERON:0001496	71.04	gold quality
metanephros cortex	UBERON:0010533	70.94	gold quality
spleen	UBERON:0002106	70.85	gold quality
popliteal artery	UBERON:0002250	70.80	gold quality
tibial artery	UBERON:0007610	70.78	gold quality
endometrium	UBERON:0001295	70.27	gold quality
cortex of kidney	UBERON:0001225	69.87	gold quality
ovary	UBERON:0000992	69.83	gold quality
right ovary	UBERON:0002118	69.75	gold quality
left ovary	UBERON:0002119	69.75	gold quality
testis	UBERON:0000473	69.64	gold quality
left testis	UBERON:0004533	69.50	gold quality
right testis	UBERON:0004534	69.04	gold quality
upper lobe of left lung	UBERON:0008952	69.03	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.70
E-ENAD-17	no	296.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.