SRRM2-AS1

Summary

SRRM2-AS1 (SRRM2 antisense RNA 1, HGNC:44162) is a long non-coding RNA gene on chromosome 16p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44162
Approved symbol	SRRM2-AS1
Name	SRRM2 antisense RNA 1
Location	16p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000205913
Ensembl biotype	lncRNA
Entrez	100128788
RNAcentral	URS000075C1D4 — lncRNA, 1371 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 39 — 39 lncRNA

ENST00000382313, ENST00000570677, ENST00000571305, ENST00000573802, ENST00000577055, ENST00000667280, ENST00000848097, ENST00000848098, ENST00000848099, ENST00000848100, ENST00000848101, ENST00000848102, ENST00000848103, ENST00000848104, ENST00000848105, ENST00000848106, ENST00000848107, ENST00000848108, ENST00000848109, ENST00000848110, ENST00000848111, ENST00000848112, ENST00000848113, ENST00000848114, ENST00000848115, ENST00000848116, ENST00000848117, ENST00000848118, ENST00000848119, ENST00000848120, ENST00000848121, ENST00000848122, ENST00000848123, ENST00000848124, ENST00000848125, ENST00000848126, ENST00000848127, ENST00000848128, ENST00000848129

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000382313 — 2 exons

Exon	Start	End
ENSE00001491683	2737480	2740804
ENSE00002658968	2737091	2737288

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 87.32.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8811 / max 16.6289, expressed in 418 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
155941	0.8811	418

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	87.32	gold quality
left testis	UBERON:0004533	87.16	gold quality
lower esophagus mucosa	UBERON:0035834	84.42	gold quality
testis	UBERON:0000473	83.31	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.58	gold quality
right uterine tube	UBERON:0001302	78.72	gold quality
bone marrow cell	CL:0002092	71.20	silver quality
sural nerve	UBERON:0015488	70.44	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.93	gold quality
right adrenal gland	UBERON:0001233	69.81	gold quality
adrenal tissue	UBERON:0018303	69.22	gold quality
right adrenal gland cortex	UBERON:0035827	69.19	gold quality
colonic epithelium	UBERON:0000397	69.17	silver quality
esophagus mucosa	UBERON:0002469	68.42	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.27	gold quality
left adrenal gland	UBERON:0001234	68.14	gold quality
stromal cell of endometrium	CL:0002255	67.32	gold quality
left adrenal gland cortex	UBERON:0035825	67.22	gold quality
ventricular zone	UBERON:0003053	66.89	gold quality
adrenal gland	UBERON:0002369	66.71	gold quality
muscle of leg	UBERON:0001383	66.53	gold quality
gastrocnemius	UBERON:0001388	66.45	gold quality
adrenal cortex	UBERON:0001235	65.73	gold quality
right lobe of liver	UBERON:0001114	65.49	gold quality
monocyte	CL:0000576	65.29	gold quality
leukocyte	CL:0000738	64.85	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.71	gold quality
granulocyte	CL:0000094	64.23	gold quality
cortical plate	UBERON:0005343	64.19	gold quality
right lobe of thyroid gland	UBERON:0001119	63.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.09

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Silencing of long noncoding RNA SRRM2-AS exerts suppressive effects on angiogenesis in nasopharyngeal carcinoma via activating MYLK-mediated cGMP-PKG signaling pathway. (PMID:31742692)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.