ST3GAL6-AS1

Summary

ST3GAL6-AS1 (ST3GAL6 antisense RNA 1, HGNC:40828) is a long non-coding RNA gene on chromosome 3q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40828
Approved symbol	ST3GAL6-AS1
Name	ST3GAL6 antisense RNA 1
Location	3q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239445
Ensembl biotype	lncRNA
Entrez	100874207
RNAcentral	URS000075A9F4 — lncRNA, 769 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000461931, ENST00000475816, ENST00000488132, ENST00000654439, ENST00000654703, ENST00000658186, ENST00000660566, ENST00000661245, ENST00000663984, ENST00000664646, ENST00000664787, ENST00000666744, ENST00000667022, ENST00000667720, ENST00000667875, ENST00000670291, ENST00000757765, ENST00000757766, ENST00000757767, ENST00000757768, ENST00000757769, ENST00000757770, ENST00000757771, ENST00000757772

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000461931 — 4 exons

Exon	Start	End
ENSE00001846519	98715305	98715521
ENSE00001913363	98715650	98715777
ENSE00001917061	98732426	98732651
ENSE00001922924	98718424	98718521

Expression profiles

Bgee: expression breadth ubiquitous, 135 present calls, max score 86.61.

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	86.61	silver quality
sural nerve	UBERON:0015488	82.61	gold quality
heart left ventricle	UBERON:0002084	75.93	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.61	gold quality
apex of heart	UBERON:0002098	75.12	gold quality
stromal cell of endometrium	CL:0002255	74.14	gold quality
heart	UBERON:0000948	73.52	gold quality
kidney	UBERON:0002113	72.25	gold quality
tibial nerve	UBERON:0001323	72.19	gold quality
adult mammalian kidney	UBERON:0000082	71.91	gold quality
right atrium auricular region	UBERON:0006631	71.84	gold quality
metanephros cortex	UBERON:0010533	71.38	gold quality
putamen	UBERON:0001874	71.12	gold quality
monocyte	CL:0000576	71.08	gold quality
leukocyte	CL:0000738	70.20	gold quality
primary visual cortex	UBERON:0002436	70.17	gold quality
spinal cord	UBERON:0002240	69.80	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	69.75	gold quality
descending thoracic aorta	UBERON:0002345	69.60	gold quality
ascending aorta	UBERON:0001496	69.56	gold quality
thoracic aorta	UBERON:0001515	69.55	gold quality
liver	UBERON:0002107	69.52	gold quality
bone marrow cell	CL:0002092	69.17	silver quality
cortex of kidney	UBERON:0001225	69.08	gold quality
amygdala	UBERON:0001876	68.72	gold quality
temporal lobe	UBERON:0001871	68.48	gold quality
hypothalamus	UBERON:0001898	67.75	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.59	gold quality
substantia nigra	UBERON:0002038	67.56	gold quality
right lobe of liver	UBERON:0001114	67.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.90

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• lncRNA ST3GAL6AS1 promotes invasion by inhibiting hnRNPA2B1mediated ST3GAL6 expression in multiple myeloma. (PMID:33649796)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.