ST7-OT4

Summary

ST7-OT4 (ST7 overlapping transcript 4, HGNC:18835) is a long non-coding RNA gene on chromosome 7q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:18835
Approved symbol	ST7-OT4
Name	ST7 overlapping transcript 4
Location	7q31.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	NCRNA00042
Ensembl gene	ENSG00000214188
Ensembl biotype	lncRNA
Entrez	338069
RNAcentral	URS0000CCE06E — lncRNA, 1627 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000397750, ENST00000397751, ENST00000466018, ENST00000470996, ENST00000471110, ENST00000597499

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000397750 — 5 exons

Exon	Start	End
ENSE00001529992	116959153	116959817
ENSE00001529993	116954461	116954679
ENSE00001529994	116953899	116954109
ENSE00001530000	116956423	116956723
ENSE00003758636	116954974	116955153

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 85.50.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3541 / max 62.7453, expressed in 113 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
204666	0.3054	110
80695	0.0488	7

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.50	gold quality
left testis	UBERON:0004533	83.29	gold quality
right testis	UBERON:0004534	82.96	gold quality
testis	UBERON:0000473	82.80	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.15	gold quality
bone marrow cell	CL:0002092	78.19	gold quality
calcaneal tendon	UBERON:0003701	76.17	gold quality
skeletal muscle tissue	UBERON:0001134	73.60	gold quality
sural nerve	UBERON:0015488	73.23	gold quality
colonic epithelium	UBERON:0000397	71.31	silver quality
corpus callosum	UBERON:0002336	69.77	gold quality
bone marrow	UBERON:0002371	68.77	gold quality
stromal cell of endometrium	CL:0002255	68.35	gold quality
adrenal tissue	UBERON:0018303	68.13	gold quality
muscle tissue	UBERON:0002385	67.93	gold quality
tonsil	UBERON:0002372	67.34	gold quality
ventricular zone	UBERON:0003053	66.88	gold quality
right uterine tube	UBERON:0001302	65.76	gold quality
right atrium auricular region	UBERON:0006631	65.63	gold quality
pituitary gland	UBERON:0000007	64.25	gold quality
heart	UBERON:0000948	63.92	gold quality
heart left ventricle	UBERON:0002084	63.01	gold quality
right coronary artery	UBERON:0001625	62.75	gold quality
ganglionic eminence	UBERON:0004023	62.61	gold quality
apex of heart	UBERON:0002098	62.46	gold quality
thyroid gland	UBERON:0002046	62.35	gold quality
liver	UBERON:0002107	62.30	gold quality
adenohypophysis	UBERON:0002196	62.10	gold quality
kidney	UBERON:0002113	61.63	gold quality
ovary	UBERON:0000992	61.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.