STEAP2-AS1

Summary

STEAP2-AS1 (STEAP2 antisense RNA 1, HGNC:40820) is a long non-coding RNA gene on chromosome 7q21.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40820
Approved symbol	STEAP2-AS1
Name	STEAP2 antisense RNA 1
Location	7q21.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227646
Ensembl biotype	lncRNA
Entrez	100874100
RNAcentral	URS000075AF5F — lncRNA, 627 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 2 lncRNA, 1 retained_intron

ENST00000433534, ENST00000478318, ENST00000718155

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433534 — 2 exons

Exon	Start	End
ENSE00001750455	90211300	90211635
ENSE00001751704	90209270	90209938

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 61.47.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	61.47	gold quality
calcaneal tendon	UBERON:0003701	59.91	gold quality
prostate gland	UBERON:0002367	58.41	gold quality
liver	UBERON:0002107	54.58	gold quality
blood	UBERON:0000178	54.39	gold quality
smooth muscle tissue	UBERON:0001135	54.23	gold quality
right lobe of liver	UBERON:0001114	54.10	gold quality
prefrontal cortex	UBERON:0000451	53.91	gold quality
gall bladder	UBERON:0002110	52.78	gold quality
islet of Langerhans	UBERON:0000006	51.96	gold quality
monocyte	CL:0000576	50.99	silver quality
primary visual cortex	UBERON:0002436	50.74	gold quality
urinary bladder	UBERON:0001255	50.66	gold quality
duodenum	UBERON:0002114	50.50	gold quality
vermiform appendix	UBERON:0001154	50.07	gold quality
lower esophagus mucosa	UBERON:0035834	49.77	gold quality
adult mammalian kidney	UBERON:0000082	49.48	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.48	gold quality
left ovary	UBERON:0002119	48.92	gold quality
kidney	UBERON:0002113	48.75	gold quality
right lung	UBERON:0002167	48.64	gold quality
ovary	UBERON:0000992	48.41	gold quality
left adrenal gland cortex	UBERON:0035825	48.26	gold quality
frontal cortex	UBERON:0001870	48.14	gold quality
cortex of kidney	UBERON:0001225	47.54	gold quality
saliva-secreting gland	UBERON:0001044	47.40	gold quality
pancreas	UBERON:0001264	47.38	gold quality
right ovary	UBERON:0002118	47.30	gold quality
minor salivary gland	UBERON:0001830	47.26	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	47.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.61

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Unsuspected Associations of Variants within the Genes NOTCH4 and STEAP2-AS1 Uncovered by a GWAS in Endemic Pemphigus Foliaceus. (PMID:33991537)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.