STX18-AS1

Summary

STX18-AS1 (STX18 antisense RNA 1, HGNC:48877) is a long non-coding RNA gene on chromosome 4p16.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48877
Approved symbol	STX18-AS1
Name	STX18 antisense RNA 1
Location	4p16.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247708
Ensembl biotype	lncRNA
OMIM	621221
Entrez	100507266
RNAcentral	URS000075B50B — lncRNA, 2481 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 38 — 38 lncRNA

ENST00000499430, ENST00000502693, ENST00000507244, ENST00000512438, ENST00000514763, ENST00000608184, ENST00000610009, ENST00000653097, ENST00000655855, ENST00000656969, ENST00000659678, ENST00000663324, ENST00000664283, ENST00000664571, ENST00000665126, ENST00000667824, ENST00000669065, ENST00000670162, ENST00000670249, ENST00000829246, ENST00000829247, ENST00000829248, ENST00000829249, ENST00000829250, ENST00000829251, ENST00000829252, ENST00000829253, ENST00000829254, ENST00000829255, ENST00000829256, ENST00000829257, ENST00000829258, ENST00000829259, ENST00000829260, ENST00000829261, ENST00000829262, ENST00000829263, ENST00000829264

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499430 — 4 exons

Exon	Start	End
ENSE00001976914	4544738	4544907
ENSE00003867205	4729827	4730211
ENSE00003870201	4542192	4542625
ENSE00003876617	4648977	4649542

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 81.66.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.7931 / max 162.8225, expressed in 1417 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46743	2.8203	1187
46744	1.9728	838

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.89	gold quality
sural nerve	UBERON:0015488	80.72	gold quality
right testis	UBERON:0004534	78.62	gold quality
left testis	UBERON:0004533	78.55	gold quality
testis	UBERON:0000473	76.56	gold quality
cortical plate	UBERON:0005343	76.48	gold quality
colonic epithelium	UBERON:0000397	74.62	gold quality
right uterine tube	UBERON:0001302	74.36	gold quality
ventricular zone	UBERON:0003053	74.35	gold quality
mucosa of transverse colon	UBERON:0004991	74.29	gold quality
ganglionic eminence	UBERON:0004023	74.25	gold quality
bone marrow cell	CL:0002092	73.49	silver quality
hindlimb stylopod muscle	UBERON:0004252	73.24	gold quality
adenohypophysis	UBERON:0002196	73.12	gold quality
ectocervix	UBERON:0012249	72.72	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.52	gold quality
apex of heart	UBERON:0002098	72.08	gold quality
left ovary	UBERON:0002119	72.02	gold quality
pituitary gland	UBERON:0000007	72.01	gold quality
granulocyte	CL:0000094	71.77	gold quality
prefrontal cortex	UBERON:0000451	71.74	gold quality
cerebellar hemisphere	UBERON:0002245	71.58	gold quality
cerebellar cortex	UBERON:0002129	71.55	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.54	gold quality
lower esophagus mucosa	UBERON:0035834	71.42	gold quality
right ovary	UBERON:0002118	71.33	gold quality
calcaneal tendon	UBERON:0003701	71.14	gold quality
body of uterus	UBERON:0009853	71.14	gold quality
anterior cingulate cortex	UBERON:0009835	70.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.