STX5-DT

Summary

STX5-DT (STX5 divergent transcript, HGNC:55488) is a long non-coding RNA gene on chromosome 11q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55488
Approved symbol	STX5-DT
Name	STX5 divergent transcript
Location	11q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256690
Ensembl biotype	lncRNA
Entrez	105369332
RNAcentral	URS00003FA36E — lncRNA, 565 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000535817, ENST00000535867, ENST00000741088

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000535817 — 2 exons

Exon	Start	End
ENSE00004077893	62832234	62832317
ENSE00004077896	62833563	62834056

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 85.00.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5721 / max 37.6472, expressed in 309 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
114751	0.5721	309

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.00	gold quality
granulocyte	CL:0000094	83.38	gold quality
bone marrow	UBERON:0002371	78.23	gold quality
left uterine tube	UBERON:0001303	77.07	gold quality
skin of abdomen	UBERON:0001416	76.78	gold quality
mucosa of transverse colon	UBERON:0004991	76.43	gold quality
right lobe of liver	UBERON:0001114	76.34	gold quality
spleen	UBERON:0002106	76.16	gold quality
left ovary	UBERON:0002119	75.94	gold quality
left testis	UBERON:0004533	75.83	gold quality
lower esophagus mucosa	UBERON:0035834	75.79	gold quality
right testis	UBERON:0004534	75.69	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.61	gold quality
testis	UBERON:0000473	75.39	gold quality
ovary	UBERON:0000992	75.13	gold quality
right ovary	UBERON:0002118	75.07	gold quality
blood	UBERON:0000178	74.68	gold quality
right uterine tube	UBERON:0001302	74.30	gold quality
bone marrow cell	CL:0002092	74.22	gold quality
omental fat pad	UBERON:0010414	74.19	gold quality
colonic epithelium	UBERON:0000397	74.07	gold quality
lymph node	UBERON:0000029	73.68	gold quality
zone of skin	UBERON:0000014	73.61	gold quality
fallopian tube	UBERON:0003889	72.91	gold quality
prostate gland	UBERON:0002367	72.89	gold quality
right lobe of thyroid gland	UBERON:0001119	72.75	gold quality
body of pancreas	UBERON:0001150	72.69	gold quality
adenohypophysis	UBERON:0002196	72.69	gold quality
esophagus mucosa	UBERON:0002469	72.45	gold quality
pituitary gland	UBERON:0000007	72.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.