SVIL-AS1

Summary

SVIL-AS1 (SVIL antisense RNA 1, HGNC:51219) is a unprocessed pseudogene on chromosome 10p11.23.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51219
Approved symbol	SVIL-AS1
Name	SVIL antisense RNA 1
Location	10p11.23
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-534G20.3
Ensembl gene	ENSG00000224597
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	102724316
RNAcentral	URS000075A1D1 — lncRNA, 3348 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000646086

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000646086 — 2 exons

Exon	Start	End
ENSE00002493112	29415357	29415412
ENSE00003979172	29409618	29409683

Expression profiles

Bgee: expression breadth ubiquitous, 210 present calls, max score 98.33.

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	98.33	gold quality
mucosa of stomach	UBERON:0001199	96.78	gold quality
left ovary	UBERON:0002119	96.60	gold quality
islet of Langerhans	UBERON:0000006	96.23	gold quality
right ovary	UBERON:0002118	96.23	gold quality
muscle layer of sigmoid colon	UBERON:0035805	96.04	gold quality
body of uterus	UBERON:0009853	95.82	gold quality
lower esophagus muscularis layer	UBERON:0035833	95.80	gold quality
lower esophagus	UBERON:0013473	95.79	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	95.49	gold quality
popliteal artery	UBERON:0002250	95.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	95.39	gold quality
tibial artery	UBERON:0007610	95.39	gold quality
gastrocnemius	UBERON:0001388	95.30	gold quality
descending thoracic aorta	UBERON:0002345	95.18	gold quality
ascending aorta	UBERON:0001496	95.12	gold quality
smooth muscle tissue	UBERON:0001135	95.11	gold quality
thoracic aorta	UBERON:0001515	95.10	gold quality
aorta	UBERON:0000947	95.05	gold quality
muscle of leg	UBERON:0001383	95.04	gold quality
endocervix	UBERON:0000458	94.72	gold quality
left adrenal gland	UBERON:0001234	94.65	gold quality
left adrenal gland cortex	UBERON:0035825	94.65	gold quality
right coronary artery	UBERON:0001625	94.63	gold quality
right adrenal gland cortex	UBERON:0035827	94.63	gold quality
right adrenal gland	UBERON:0001233	94.50	gold quality
ectocervix	UBERON:0012249	94.50	gold quality
left uterine tube	UBERON:0001303	94.44	gold quality
left coronary artery	UBERON:0001626	94.32	gold quality
tibial nerve	UBERON:0001323	94.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.48

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• N6-methyladenosine-induced SVIL antisense RNA 1 restrains lung adenocarcinoma cell proliferation by destabilizing E2F1. (PMID:35068325)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.