SYNE1-AS2
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Summary
SYNE1-AS2 (SYNE1 antisense RNA 2, HGNC:40794) is a long non-coding RNA gene on chromosome 6q25.2.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:40794 |
| Approved symbol | SYNE1-AS2 |
| Name | SYNE1 antisense RNA 2 |
| Location | 6q25.2 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000226193 |
| Ensembl biotype | lncRNA |
| Entrez | 124901437 |
Gene structure
Transcript identifiers
Ensembl transcripts: 2 — 2 lncRNA
ENST00000458194, ENST00000832503
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000458194 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00004248050 | 152404852 | 152404967 |
| ENSE00004248051 | 152402155 | 152402667 |
Expression profiles
Bgee: expression breadth broad, 88 present calls, max score 74.45.
Top tissues by expression
88 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| uterine cervix | UBERON:0000002 | 74.45 | silver quality |
| sural nerve | UBERON:0015488 | 68.52 | silver quality |
| skeletal muscle tissue | UBERON:0001134 | 68.20 | silver quality |
| metanephros cortex | UBERON:0010533 | 68.01 | gold quality |
| cortex of kidney | UBERON:0001225 | 65.99 | gold quality |
| kidney | UBERON:0002113 | 64.07 | gold quality |
| adult mammalian kidney | UBERON:0000082 | 64.05 | gold quality |
| urinary bladder | UBERON:0001255 | 63.65 | silver quality |
| descending thoracic aorta | UBERON:0002345 | 60.01 | gold quality |
| ascending aorta | UBERON:0001496 | 59.98 | gold quality |
| thoracic aorta | UBERON:0001515 | 59.97 | gold quality |
| islet of Langerhans | UBERON:0000006 | 59.16 | gold quality |
| popliteal artery | UBERON:0002250 | 57.76 | gold quality |
| tibial artery | UBERON:0007610 | 57.69 | gold quality |
| left coronary artery | UBERON:0001626 | 57.01 | gold quality |
| adrenal tissue | UBERON:0018303 | 56.63 | gold quality |
| blood | UBERON:0000178 | 56.40 | gold quality |
| corpus callosum | UBERON:0002336 | 54.11 | gold quality |
| right coronary artery | UBERON:0001625 | 54.06 | gold quality |
| gastrocnemius | UBERON:0001388 | 53.73 | gold quality |
| calcaneal tendon | UBERON:0003701 | 53.64 | gold quality |
| liver | UBERON:0002107 | 53.61 | gold quality |
| monocyte | CL:0000576 | 53.33 | silver quality |
| heart | UBERON:0000948 | 52.60 | gold quality |
| multicellular organism | UBERON:0000468 | 50.49 | gold quality |
| adrenal gland | UBERON:0002369 | 49.62 | gold quality |
| left adrenal gland cortex | UBERON:0035825 | 49.19 | gold quality |
| left adrenal gland | UBERON:0001234 | 48.73 | gold quality |
| myometrium | UBERON:0001296 | 48.55 | gold quality |
| heart left ventricle | UBERON:0002084 | 48.46 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.97 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): autosomal recessive ataxia, Beauce type, Emery-Dreifuss muscular dystrophy 4, autosomal dominant