SYNGAP1-AS1

Summary

SYNGAP1-AS1 (SYNGAP1 antisense RNA 1, HGNC:53831) is a long non-coding RNA gene on chromosome 6p21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53831
Approved symbol	SYNGAP1-AS1
Name	SYNGAP1 antisense RNA 1
Location	6p21.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	SYNGAP1-AS
Ensembl gene	ENSG00000274259
Ensembl biotype	lncRNA
Entrez	112390310
RNAcentral	URS00025E34C0 — lncRNA, 448 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000614205, ENST00000630418, ENST00000815438, ENST00000815439

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000614205 — 1 exons

Exon	Start	End
ENSE00004217437	33453662	33454470

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 93.53.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6370 / max 39.9712, expressed in 364 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
73168	0.6370	364

Top tissues by expression

136 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	93.53	silver quality
sural nerve	UBERON:0015488	91.99	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.70	gold quality
pituitary gland	UBERON:0000007	77.63	gold quality
adenohypophysis	UBERON:0002196	74.35	gold quality
colonic epithelium	UBERON:0000397	72.05	gold quality
cortical plate	UBERON:0005343	71.76	gold quality
right uterine tube	UBERON:0001302	70.96	gold quality
bone marrow cell	CL:0002092	70.50	silver quality
quadriceps femoris	UBERON:0001377	70.45	gold quality
ganglionic eminence	UBERON:0004023	69.94	gold quality
ventricular zone	UBERON:0003053	68.10	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
superior frontal gyrus	UBERON:0002661	67.68	gold quality
granulocyte	CL:0000094	67.45	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.84	gold quality
tonsil	UBERON:0002372	66.28	gold quality
heart left ventricle	UBERON:0002084	66.22	gold quality
right testis	UBERON:0004534	66.14	gold quality
placenta	UBERON:0001987	65.73	gold quality
left testis	UBERON:0004533	65.52	gold quality
testis	UBERON:0000473	65.15	gold quality
prefrontal cortex	UBERON:0000451	64.79	gold quality
left ovary	UBERON:0002119	64.79	gold quality
right lobe of thyroid gland	UBERON:0001119	64.67	gold quality
ovary	UBERON:0000992	64.60	gold quality
right coronary artery	UBERON:0001625	64.59	gold quality
thyroid gland	UBERON:0002046	64.59	gold quality
right ovary	UBERON:0002118	64.48	gold quality
blood	UBERON:0000178	64.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.