SYNM-AS1

Summary

SYNM-AS1 (SYNM antisense RNA 1, HGNC:55421) is a long non-coding RNA gene on chromosome 15q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55421
Approved symbol	SYNM-AS1
Name	SYNM antisense RNA 1
Location	15q26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259475
Ensembl biotype	lncRNA
Entrez	105371016
RNAcentral	URS00026A21C0 — lncRNA, 526 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000559468, ENST00000830103, ENST00000838383

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000559468 — 4 exons

Exon	Start	End
ENSE00002553798	99100723	99100851
ENSE00002557994	98954149	98954388
ENSE00002559482	98965989	98966070
ENSE00002567416	99105688	99105824

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 88.08.

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.08	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.74	silver quality
hindlimb stylopod muscle	UBERON:0004252	72.35	gold quality
skeletal muscle tissue	UBERON:0001134	69.77	gold quality
muscle of leg	UBERON:0001383	69.05	gold quality
lower esophagus muscularis layer	UBERON:0035833	69.02	gold quality
lower esophagus	UBERON:0013473	68.92	gold quality
gastrocnemius	UBERON:0001388	68.56	gold quality
bone marrow	UBERON:0002371	68.09	gold quality
cortical plate	UBERON:0005343	63.64	gold quality
popliteal artery	UBERON:0002250	63.02	gold quality
tibial artery	UBERON:0007610	63.00	gold quality
ganglionic eminence	UBERON:0004023	62.43	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	62.03	gold quality
esophagus	UBERON:0001043	61.66	gold quality
blood	UBERON:0000178	61.55	gold quality
lower esophagus mucosa	UBERON:0035834	59.11	gold quality
right coronary artery	UBERON:0001625	58.94	gold quality
urinary bladder	UBERON:0001255	58.78	gold quality
right atrium auricular region	UBERON:0006631	58.51	gold quality
smooth muscle tissue	UBERON:0001135	58.02	gold quality
descending thoracic aorta	UBERON:0002345	57.86	gold quality
ascending aorta	UBERON:0001496	57.70	gold quality
thoracic aorta	UBERON:0001515	57.58	gold quality
right uterine tube	UBERON:0001302	57.29	gold quality
adrenal tissue	UBERON:0018303	57.02	gold quality
left coronary artery	UBERON:0001626	56.91	gold quality
right lung	UBERON:0002167	56.69	gold quality
leukocyte	CL:0000738	56.22	gold quality
left ovary	UBERON:0002119	56.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.75

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.