SYNM-AS2

Summary

SYNM-AS2 (SYNM antisense RNA 2, HGNC:56228) is a long non-coding RNA gene on chromosome 15q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56228
Approved symbol	SYNM-AS2
Name	SYNM antisense RNA 2
Location	15q26.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	TP53LC11
Ensembl gene	ENSG00000261054
Ensembl biotype	lncRNA
Entrez	125177379
RNAcentral	URS0000585837 — lncRNA, 2562 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000566974

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000566974 — 2 exons

Exon	Start	End
ENSE00002581888	99128832	99130389
ENSE00002601413	99130803	99131806

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 83.77.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	83.77	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.20	gold quality
colonic epithelium	UBERON:0000397	77.05	gold quality
skeletal muscle tissue	UBERON:0001134	76.37	gold quality
lower esophagus muscularis layer	UBERON:0035833	73.73	gold quality
lower esophagus	UBERON:0013473	73.62	gold quality
urinary bladder	UBERON:0001255	73.28	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	72.35	gold quality
mucosa of stomach	UBERON:0001199	71.94	gold quality
calcaneal tendon	UBERON:0003701	71.34	gold quality
muscle layer of sigmoid colon	UBERON:0035805	70.69	gold quality
popliteal artery	UBERON:0002250	70.66	gold quality
tibial artery	UBERON:0007610	70.64	gold quality
muscle of leg	UBERON:0001383	66.25	gold quality
gastrocnemius	UBERON:0001388	66.12	gold quality
tonsil	UBERON:0002372	65.05	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.87	gold quality
thoracic mammary gland	UBERON:0005200	63.83	gold quality
colon	UBERON:0001155	63.61	gold quality
esophagus	UBERON:0001043	63.41	gold quality
right atrium auricular region	UBERON:0006631	62.98	gold quality
smooth muscle tissue	UBERON:0001135	62.78	gold quality
cortical plate	UBERON:0005343	62.10	silver quality
prostate gland	UBERON:0002367	61.83	gold quality
duodenum	UBERON:0002114	61.59	gold quality
intestine	UBERON:0000160	61.02	gold quality
left uterine tube	UBERON:0001303	59.84	gold quality
heart	UBERON:0000948	59.52	gold quality
vermiform appendix	UBERON:0001154	58.77	gold quality
heart left ventricle	UBERON:0002084	58.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.