SYNPO2L-AS1

Summary

SYNPO2L-AS1 (SYNPO2L antisense RNA 1, HGNC:55242) is a long non-coding RNA gene on chromosome 10q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55242
Approved symbol	SYNPO2L-AS1
Name	SYNPO2L antisense RNA 1
Location	10q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000271848
Ensembl biotype	lncRNA
Entrez	105378360
RNAcentral	URS00026A256C — lncRNA, 1231 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 25 lncRNA

ENST00000606726, ENST00000607450, ENST00000654036, ENST00000668336, ENST00000759288, ENST00000759289, ENST00000759290, ENST00000759291, ENST00000759292, ENST00000759293, ENST00000759294, ENST00000759295, ENST00000759296, ENST00000759297, ENST00000759298, ENST00000759299, ENST00000759300, ENST00000759301, ENST00000759302, ENST00000759303, ENST00000759304, ENST00000759305, ENST00000759306, ENST00000759307, ENST00000759308

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606726 — 4 exons

Exon	Start	End
ENSE00004111886	73674573	73675452
ENSE00004111887	73653959	73654306
ENSE00004111902	73647559	73647677
ENSE00004111907	73667726	73668361

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 77.13.

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.52	silver quality
skeletal muscle tissue	UBERON:0001134	74.46	gold quality
apex of heart	UBERON:0002098	73.56	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.06	gold quality
heart left ventricle	UBERON:0002084	71.90	gold quality
right atrium auricular region	UBERON:0006631	70.79	gold quality
heart	UBERON:0000948	69.06	gold quality
sural nerve	UBERON:0015488	68.31	gold quality
muscle of leg	UBERON:0001383	67.27	gold quality
gastrocnemius	UBERON:0001388	65.31	gold quality
cortical plate	UBERON:0005343	63.00	gold quality
ventricular zone	UBERON:0003053	62.56	gold quality
stromal cell of endometrium	CL:0002255	62.42	gold quality
blood	UBERON:0000178	58.94	gold quality
ganglionic eminence	UBERON:0004023	57.95	gold quality
endometrium	UBERON:0001295	56.75	gold quality
putamen	UBERON:0001874	56.67	gold quality
caudate nucleus	UBERON:0001873	56.42	gold quality
temporal lobe	UBERON:0001871	55.71	gold quality
prefrontal cortex	UBERON:0000451	55.63	gold quality
nucleus accumbens	UBERON:0001882	55.60	gold quality
amygdala	UBERON:0001876	55.42	gold quality
body of uterus	UBERON:0009853	54.45	gold quality
cortex of kidney	UBERON:0001225	54.31	gold quality
myometrium	UBERON:0001296	54.02	gold quality
islet of Langerhans	UBERON:0000006	54.00	gold quality
uterine cervix	UBERON:0000002	53.71	gold quality
liver	UBERON:0002107	53.70	silver quality
left ovary	UBERON:0002119	53.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.