SYT1-AS1

Summary

SYT1-AS1 (SYT1 antisense RNA 1, HGNC:58105) is a long non-coding RNA gene on chromosome 12q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58105
Approved symbol	SYT1-AS1
Name	SYT1 antisense RNA 1
Location	12q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC027288.3
Ensembl gene	ENSG00000257894
Ensembl biotype	lncRNA
Entrez	137805486
RNAcentral	URS0002A61D34 — lncRNA, 1892 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000549527, ENST00000550268, ENST00000553165, ENST00000774245

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000549527 — 2 exons

Exon	Start	End
ENSE00002392749	79503169	79503396
ENSE00002420865	79341205	79341409

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 91.46.

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
decidua	UBERON:0002450	91.46	gold quality
germinal epithelium of ovary	UBERON:0001304	84.24	gold quality
parietal pleura	UBERON:0002400	81.78	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.44	gold quality
stromal cell of endometrium	CL:0002255	78.57	gold quality
left ovary	UBERON:0002119	77.53	gold quality
visceral pleura	UBERON:0002401	77.29	gold quality
sural nerve	UBERON:0015488	74.16	gold quality
ovary	UBERON:0000992	73.18	gold quality
right lung	UBERON:0002167	72.08	gold quality
cortical plate	UBERON:0005343	71.89	gold quality
colonic epithelium	UBERON:0000397	71.54	gold quality
upper lobe of left lung	UBERON:0008952	70.75	gold quality
right ovary	UBERON:0002118	70.46	gold quality
upper lobe of lung	UBERON:0008948	70.19	gold quality
lung	UBERON:0002048	69.88	gold quality
kidney epithelium	UBERON:0004819	68.43	silver quality
tibial nerve	UBERON:0001323	67.55	gold quality
smooth muscle tissue	UBERON:0001135	67.26	gold quality
adult mammalian kidney	UBERON:0000082	65.79	gold quality
kidney	UBERON:0002113	65.71	gold quality
omental fat pad	UBERON:0010414	65.61	gold quality
peritoneum	UBERON:0002358	65.54	gold quality
bone marrow cell	CL:0002092	65.21	silver quality
endometrium	UBERON:0001295	64.38	gold quality
adipose tissue of abdominal region	UBERON:0007808	64.19	gold quality
right coronary artery	UBERON:0001625	63.99	gold quality
lower lobe of lung	UBERON:0008949	63.99	silver quality
gall bladder	UBERON:0002110	63.95	gold quality
myometrium	UBERON:0001296	63.34	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	56.65
E-ANND-3	yes	4.38

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.