SYT2-AS1

Summary

SYT2-AS1 (SYT2 antisense RNA 1, HGNC:40572) is a long non-coding RNA gene on chromosome 1q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40572
Approved symbol	SYT2-AS1
Name	SYT2 antisense RNA 1
Location	1q32.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-569A11.1
Ensembl gene	ENSG00000226862
Ensembl biotype	lncRNA
Entrez	129810494
RNAcentral	URS00005BA32A — lncRNA, 314 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000428573

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428573 — 2 exons

Exon	Start	End
ENSE00001621113	202605048	202605293
ENSE00001754222	202604268	202604335

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 90.13.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.13	gold quality
right coronary artery	UBERON:0001625	85.17	gold quality
mucosa of stomach	UBERON:0001199	84.16	gold quality
ascending aorta	UBERON:0001496	83.15	gold quality
thoracic aorta	UBERON:0001515	82.93	gold quality
colonic epithelium	UBERON:0000397	82.78	gold quality
body of uterus	UBERON:0009853	81.94	gold quality
popliteal artery	UBERON:0002250	81.34	gold quality
tibial artery	UBERON:0007610	81.34	gold quality
muscle layer of sigmoid colon	UBERON:0035805	80.74	gold quality
left coronary artery	UBERON:0001626	80.47	gold quality
myometrium	UBERON:0001296	80.44	gold quality
heart left ventricle	UBERON:0002084	80.29	gold quality
descending thoracic aorta	UBERON:0002345	80.07	gold quality
apex of heart	UBERON:0002098	79.53	gold quality
heart	UBERON:0000948	78.94	gold quality
smooth muscle tissue	UBERON:0001135	78.64	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	78.61	gold quality
lower esophagus muscularis layer	UBERON:0035833	78.35	gold quality
lower esophagus	UBERON:0013473	78.33	gold quality
left uterine tube	UBERON:0001303	78.30	gold quality
right atrium auricular region	UBERON:0006631	78.20	gold quality
lower esophagus mucosa	UBERON:0035834	78.11	gold quality
fundus of stomach	UBERON:0001160	77.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	77.67	gold quality
cerebellar hemisphere	UBERON:0002245	77.28	gold quality
cerebellar cortex	UBERON:0002129	77.08	gold quality
right hemisphere of cerebellum	UBERON:0014890	76.99	gold quality
cerebellum	UBERON:0002037	76.81	gold quality
prostate gland	UBERON:0002367	76.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.21

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Super-enhancer-associated long noncoding RNA RP11-569A11.1 inhibited cell progression and metastasis by regulating IFIT2 in colorectal cancer. (PMID:33942366)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.