TAB2-AS1

Summary

TAB2-AS1 (TAB2 antisense RNA 1, HGNC:53508) is a long non-coding RNA gene on chromosome 6q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53508
Approved symbol	TAB2-AS1
Name	TAB2 antisense RNA 1
Location	6q25.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225924
Ensembl biotype	lncRNA
Entrez	105378049
RNAcentral	URS0000BC461A — lncRNA, 746 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000424421, ENST00000637865, ENST00000844513

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424421 — 3 exons

Exon	Start	End
ENSE00001684120	149243626	149244001
ENSE00004271327	149257384	149257557
ENSE00004271330	149243282	149243484

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 95.72.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.72	gold quality
left testis	UBERON:0004533	67.52	gold quality
testis	UBERON:0000473	66.68	gold quality
right testis	UBERON:0004534	65.28	gold quality
endometrium	UBERON:0001295	55.70	silver quality
prefrontal cortex	UBERON:0000451	55.43	gold quality
corpus callosum	UBERON:0002336	53.84	gold quality
monocyte	CL:0000576	53.19	silver quality
Brodmann (1909) area 9	UBERON:0013540	53.16	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.02	gold quality
lymph node	UBERON:0000029	52.99	gold quality
amygdala	UBERON:0001876	52.88	gold quality
blood	UBERON:0000178	52.00	gold quality
multicellular organism	UBERON:0000468	51.97	gold quality
gall bladder	UBERON:0002110	51.28	gold quality
superior frontal gyrus	UBERON:0002661	51.15	gold quality
substantia nigra	UBERON:0002038	50.86	gold quality
anterior cingulate cortex	UBERON:0009835	50.74	gold quality
granulocyte	CL:0000094	50.72	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	50.59	gold quality
Ammon’s horn	UBERON:0001954	50.44	gold quality
cerebral cortex	UBERON:0000956	50.36	gold quality
caudate nucleus	UBERON:0001873	50.15	gold quality
frontal cortex	UBERON:0001870	50.01	gold quality
brain	UBERON:0000955	49.62	gold quality
cerebellar hemisphere	UBERON:0002245	49.17	gold quality
cerebellar cortex	UBERON:0002129	49.02	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	48.85	silver quality
skin of abdomen	UBERON:0001416	48.54	gold quality
tonsil	UBERON:0002372	48.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.