TANAR

Summary

TANAR (TWIST1 associated long noncoding RNA regulated by androgen receptor, HGNC:56695) is a long non-coding RNA gene on chromosome 2q37.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56695
Approved symbol	TANAR
Name	TWIST1 associated long noncoding RNA regulated by androgen receptor
Location	2q37.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223991
Ensembl biotype	lncRNA
Entrez	128266846
RNAcentral	URS00026A2847 — lncRNA, 2410 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000425110

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425110 — 2 exons

Exon	Start	End
ENSE00001648751	240985899	240986072
ENSE00001732916	240981515	240983685

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 92.20.

Top tissues by expression

85 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	92.20	gold quality
right lobe of liver	UBERON:0001114	82.86	gold quality
liver	UBERON:0002107	79.42	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.72	gold quality
fallopian tube	UBERON:0003889	61.15	gold quality
spleen	UBERON:0002106	59.12	gold quality
endometrium	UBERON:0001295	58.87	gold quality
Brodmann (1909) area 9	UBERON:0013540	58.87	gold quality
prefrontal cortex	UBERON:0000451	57.45	gold quality
left uterine tube	UBERON:0001303	57.10	gold quality
nucleus accumbens	UBERON:0001882	55.86	gold quality
caudate nucleus	UBERON:0001873	55.45	gold quality
granulocyte	CL:0000094	54.56	gold quality
amygdala	UBERON:0001876	53.00	gold quality
Ammon’s horn	UBERON:0001954	52.78	gold quality
hypothalamus	UBERON:0001898	52.40	gold quality
upper lobe of left lung	UBERON:0008952	51.72	gold quality
lung	UBERON:0002048	51.56	gold quality
endocervix	UBERON:0000458	51.54	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	51.51	gold quality
adrenal tissue	UBERON:0018303	51.50	gold quality
lymph node	UBERON:0000029	51.27	silver quality
urinary bladder	UBERON:0001255	51.10	gold quality
blood	UBERON:0000178	50.87	gold quality
pancreas	UBERON:0001264	50.19	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	49.93	gold quality
thoracic mammary gland	UBERON:0005200	49.84	gold quality
myometrium	UBERON:0001296	49.66	gold quality
monocyte	CL:0000576	48.86	silver quality
multicellular organism	UBERON:0000468	48.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.32

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Androgen receptor promotes renal cell carcinoma (RCC) vasculogenic mimicry (VM) via altering TWIST1 nonsense-mediated decay through lncRNA-TANAR. (PMID:33510354)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.