TANGO2-AS1

Summary

TANGO2-AS1 (TANGO2 antisense RNA 1, HGNC:41096) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41096
Approved symbol	TANGO2-AS1
Name	TANGO2 antisense RNA 1
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236540
Ensembl biotype	lncRNA
Entrez	141585751

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000415503, ENST00000595864, ENST00000596334, ENST00000598339, ENST00000600617, ENST00000600937, ENST00000601746, ENST00000608610, ENST00000609191, ENST00000609644, ENST00000628442

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415503 — 3 exons

Exon	Start	End
ENSE00001592670	20065146	20065280
ENSE00001681762	20062980	20063153
ENSE00001725904	20065879	20066077

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 87.55.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	87.55	gold quality
apex of heart	UBERON:0002098	85.72	gold quality
sural nerve	UBERON:0015488	85.30	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.87	gold quality
monocyte	CL:0000576	82.02	gold quality
spleen	UBERON:0002106	81.78	gold quality
leukocyte	CL:0000738	81.67	gold quality
heart left ventricle	UBERON:0002084	81.47	gold quality
granulocyte	CL:0000094	80.75	gold quality
bone marrow cell	CL:0002092	80.24	gold quality
right atrium auricular region	UBERON:0006631	80.11	gold quality
right lobe of thyroid gland	UBERON:0001119	80.04	gold quality
bone marrow	UBERON:0002371	79.89	gold quality
left lobe of thyroid gland	UBERON:0001120	79.80	gold quality
heart	UBERON:0000948	79.76	gold quality
thyroid gland	UBERON:0002046	79.37	gold quality
hindlimb stylopod muscle	UBERON:0004252	78.75	gold quality
vermiform appendix	UBERON:0001154	78.58	gold quality
right coronary artery	UBERON:0001625	78.18	gold quality
gastrocnemius	UBERON:0001388	78.09	gold quality
mucosa of stomach	UBERON:0001199	77.72	gold quality
lymph node	UBERON:0000029	77.70	gold quality
body of stomach	UBERON:0001161	77.62	gold quality
muscle of leg	UBERON:0001383	77.30	gold quality
metanephros cortex	UBERON:0010533	77.29	gold quality
right lung	UBERON:0002167	77.26	gold quality
subcutaneous adipose tissue	UBERON:0002190	77.20	gold quality
right adrenal gland cortex	UBERON:0035827	77.17	gold quality
right adrenal gland	UBERON:0001233	77.09	gold quality
upper lobe of left lung	UBERON:0008952	76.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.83

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.