TANK-AS1

Summary

TANK-AS1 (TANK antisense RNA 1, HGNC:40575) is a long non-coding RNA gene on chromosome 2q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40575
Approved symbol	TANK-AS1
Name	TANK antisense RNA 1
Location	2q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224467
Ensembl biotype	lncRNA
Entrez	105373719
RNAcentral	URS00026A24B0 — lncRNA, 708 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000425470

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425470 — 3 exons

Exon	Start	End
ENSE00001485239	161096231	161096568
ENSE00001636649	161160132	161160224
ENSE00001791366	161159165	161159236

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 92.29.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.29	gold quality
bone marrow cell	CL:0002092	74.05	gold quality
bone marrow	UBERON:0002371	66.56	gold quality
ganglionic eminence	UBERON:0004023	65.30	gold quality
islet of Langerhans	UBERON:0000006	60.92	gold quality
monocyte	CL:0000576	60.84	gold quality
left testis	UBERON:0004533	59.51	gold quality
testis	UBERON:0000473	59.49	gold quality
right testis	UBERON:0004534	58.41	gold quality
calcaneal tendon	UBERON:0003701	56.30	gold quality
gall bladder	UBERON:0002110	56.18	gold quality
prefrontal cortex	UBERON:0000451	55.01	gold quality
granulocyte	CL:0000094	53.64	gold quality
primary visual cortex	UBERON:0002436	53.52	gold quality
blood	UBERON:0000178	53.17	gold quality
lymph node	UBERON:0000029	51.94	gold quality
tonsil	UBERON:0002372	51.42	gold quality
fundus of stomach	UBERON:0001160	51.17	gold quality
vagina	UBERON:0000996	50.95	gold quality
multicellular organism	UBERON:0000468	49.61	gold quality
gastrocnemius	UBERON:0001388	48.23	gold quality
cortex of kidney	UBERON:0001225	47.40	gold quality
Ammon’s horn	UBERON:0001954	47.14	gold quality
heart left ventricle	UBERON:0002084	46.86	gold quality
right hemisphere of cerebellum	UBERON:0014890	46.34	silver quality
heart	UBERON:0000948	45.86	gold quality
thoracic mammary gland	UBERON:0005200	45.72	silver quality
cerebellar hemisphere	UBERON:0002245	45.58	silver quality
left uterine tube	UBERON:0001303	44.71	gold quality
rectum	UBERON:0001052	44.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.