TAT-AS1

Summary

TAT-AS1 (TAT antisense RNA 1, HGNC:51369) is a long non-coding RNA gene on chromosome 16q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51369
Approved symbol	TAT-AS1
Name	TAT antisense RNA 1
Location	16q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260886
Ensembl biotype	lncRNA
Entrez	100132529
RNAcentral	URS000075B8BC — lncRNA, 711 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000561529, ENST00000656895, ENST00000666821, ENST00000670228, ENST00000760518, ENST00000760519

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561529 — 4 exons

Exon	Start	End
ENSE00002588724	71578065	71578187
ENSE00002609699	71565789	71565921
ENSE00002624959	71572020	71572485
ENSE00002627326	71566051	71566201

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 84.91.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2685 / max 41.9509, expressed in 111 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
154923	0.2366	104
154922	0.0319	6

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	84.91	gold quality
testis	UBERON:0000473	84.35	gold quality
right testis	UBERON:0004534	84.35	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.72	gold quality
right lobe of liver	UBERON:0001114	82.35	gold quality
liver	UBERON:0002107	81.67	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	73.46	gold quality
islet of Langerhans	UBERON:0000006	68.64	gold quality
muscle tissue	UBERON:0002385	68.18	gold quality
right uterine tube	UBERON:0001302	66.51	gold quality
cortical plate	UBERON:0005343	61.86	gold quality
gall bladder	UBERON:0002110	60.34	gold quality
thoracic mammary gland	UBERON:0005200	59.76	gold quality
ventricular zone	UBERON:0003053	59.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.23	gold quality
pancreas	UBERON:0001264	59.12	gold quality
ganglionic eminence	UBERON:0004023	57.08	gold quality
mucosa of transverse colon	UBERON:0004991	56.91	gold quality
duodenum	UBERON:0002114	56.77	gold quality
right lung	UBERON:0002167	56.25	gold quality
lymph node	UBERON:0000029	55.92	gold quality
subcutaneous adipose tissue	UBERON:0002190	54.41	gold quality
fallopian tube	UBERON:0003889	53.97	gold quality
body of pancreas	UBERON:0001150	53.13	gold quality
adipose tissue	UBERON:0001013	52.68	gold quality
blood	UBERON:0000178	52.25	gold quality
adenohypophysis	UBERON:0002196	51.34	gold quality
prefrontal cortex	UBERON:0000451	51.08	gold quality
pituitary gland	UBERON:0000007	50.96	gold quality
multicellular organism	UBERON:0000468	50.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.