TBC1D22A-AS1

Summary

TBC1D22A-AS1 (TBC1D22A antisense RNA 1, HGNC:51221) is a long non-coding RNA gene on chromosome 22q13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51221
Approved symbol	TBC1D22A-AS1
Name	TBC1D22A antisense RNA 1
Location	22q13.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000280080
Ensembl biotype	lncRNA
Entrez	642757
RNAcentral	URS000075BF8C — lncRNA, 1972 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000625149, ENST00000640274

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000625149 — 1 exons

Exon	Start	End
ENSE00003759571	46915328	46915908

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 79.18.

Top tissues by expression

204 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	79.18	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.78	gold quality
bone marrow cell	CL:0002092	74.52	gold quality
colonic epithelium	UBERON:0000397	72.93	gold quality
sural nerve	UBERON:0015488	70.74	gold quality
ganglionic eminence	UBERON:0004023	66.59	gold quality
cortical plate	UBERON:0005343	63.84	gold quality
right testis	UBERON:0004534	61.24	gold quality
left testis	UBERON:0004533	59.21	gold quality
testis	UBERON:0000473	57.89	gold quality
tonsil	UBERON:0002372	57.68	silver quality
monocyte	CL:0000576	57.19	gold quality
adrenal tissue	UBERON:0018303	55.57	gold quality
calcaneal tendon	UBERON:0003701	54.25	silver quality
lower lobe of lung	UBERON:0008949	53.37	silver quality
nasal cavity epithelium	UBERON:0005384	53.10	gold quality
uterine cervix	UBERON:0000002	52.37	silver quality
blood	UBERON:0000178	51.53	gold quality
prefrontal cortex	UBERON:0000451	50.82	gold quality
bone marrow	UBERON:0002371	50.65	silver quality
hindlimb stylopod muscle	UBERON:0004252	49.96	silver quality
sperm	CL:0000019	49.82	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.75	gold quality
right lobe of liver	UBERON:0001114	48.67	gold quality
islet of Langerhans	UBERON:0000006	48.60	gold quality
tendon	UBERON:0000043	48.50	silver quality
liver	UBERON:0002107	48.08	silver quality
muscle of leg	UBERON:0001383	47.94	silver quality
pancreas	UBERON:0001264	47.18	gold quality
right hemisphere of cerebellum	UBERON:0014890	47.17	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.