TBX18-AS1

Summary

TBX18-AS1 (TBX18 antisense RNA 1, HGNC:52256) is a long non-coding RNA gene on chromosome 6q14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52256
Approved symbol	TBX18-AS1
Name	TBX18 antisense RNA 1
Location	6q14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228290
Ensembl biotype	lncRNA
Entrez	102724201
RNAcentral	URS00007E416C — lncRNA, 604 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000423086, ENST00000441863, ENST00000586398, ENST00000586938, ENST00000587281, ENST00000589304, ENST00000590270, ENST00000591225, ENST00000592681, ENST00000620850, ENST00000626169, ENST00000658089, ENST00000810471

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423086 — 3 exons

Exon	Start	End
ENSE00001689999	84695056	84695108
ENSE00004207361	84689435	84689561
ENSE00004207364	84709268	84709578

Expression profiles

Bgee: expression breadth ubiquitous, 142 present calls, max score 92.10.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0113 / max 9.9857, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
68796	0.0113	3

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	92.10	gold quality
right testis	UBERON:0004534	91.53	gold quality
testis	UBERON:0000473	88.75	gold quality
sperm	CL:0000019	88.01	gold quality
right coronary artery	UBERON:0001625	83.76	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.36	gold quality
tibial artery	UBERON:0007610	81.62	gold quality
popliteal artery	UBERON:0002250	81.59	gold quality
left coronary artery	UBERON:0001626	81.01	gold quality
descending thoracic aorta	UBERON:0002345	80.66	gold quality
aorta	UBERON:0000947	79.92	gold quality
coronary artery	UBERON:0001621	79.03	gold quality
calcaneal tendon	UBERON:0003701	78.70	gold quality
thoracic aorta	UBERON:0001515	78.23	gold quality
ascending aorta	UBERON:0001496	77.86	gold quality
sural nerve	UBERON:0015488	72.84	gold quality
colonic epithelium	UBERON:0000397	68.07	gold quality
tibial nerve	UBERON:0001323	66.75	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.08	gold quality
apex of heart	UBERON:0002098	66.05	gold quality
tendon	UBERON:0000043	65.69	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.04	gold quality
lower esophagus	UBERON:0013473	65.03	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.48	gold quality
kidney epithelium	UBERON:0004819	63.98	gold quality
right atrium auricular region	UBERON:0006631	63.93	gold quality
ganglionic eminence	UBERON:0004023	63.39	gold quality
cardiac atrium	UBERON:0002081	63.06	gold quality
adult organism	UBERON:0007023	62.73	silver quality
heart	UBERON:0000948	62.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.