TBX2-AS1

Summary

TBX2-AS1 (TBX2 antisense RNA 1, HGNC:50355) is a long non-coding RNA gene on chromosome 17q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50355
Approved symbol	TBX2-AS1
Name	TBX2 antisense RNA 1
Location	17q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267280
Ensembl biotype	lncRNA
Entrez	103689912
RNAcentral	URS00007E4A0B — lncRNA, 862 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 60 — 60 lncRNA

ENST00000585765, ENST00000586706, ENST00000589814, ENST00000590421, ENST00000591313, ENST00000592009, ENST00000592377, ENST00000717203, ENST00000717204, ENST00000722629, ENST00000722630, ENST00000722631, ENST00000722632, ENST00000722633, ENST00000722634, ENST00000722635, ENST00000722636, ENST00000722637, ENST00000722638, ENST00000722639, ENST00000722640, ENST00000722641, ENST00000722642, ENST00000722643, ENST00000722644, ENST00000722645, ENST00000722646, ENST00000722647, ENST00000722648, ENST00000722649, ENST00000722650, ENST00000722651, ENST00000722652, ENST00000722653, ENST00000722654, ENST00000722655, ENST00000722656, ENST00000722657, ENST00000722658, ENST00000722659, ENST00000722660, ENST00000722661, ENST00000722662, ENST00000722663, ENST00000722664, ENST00000722665, ENST00000722666, ENST00000722667, ENST00000722668, ENST00000722669, ENST00000722670, ENST00000722671, ENST00000722672, ENST00000722673, ENST00000722674, ENST00000722675, ENST00000722676, ENST00000722677, ENST00000722678, ENST00000722679

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000585765 — 4 exons

Exon	Start	End
ENSE00002762050	61400216	61400243
ENSE00002784910	61367526	61367704
ENSE00002930669	61361668	61361857
ENSE00002938448	61362733	61362805

Expression profiles

Bgee: expression breadth ubiquitous, 177 present calls, max score 96.78.

FANTOM5 (CAGE): breadth broad, TPM avg 5.1488 / max 114.3235, expressed in 838 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
167395	4.3938	815
167393	0.5035	123
167394	0.1465	90
208298	0.1050	58

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	96.78	gold quality
corpus epididymis	UBERON:0004359	96.78	gold quality
right coronary artery	UBERON:0001625	94.37	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	93.81	gold quality
right lung	UBERON:0002167	93.20	gold quality
left coronary artery	UBERON:0001626	93.06	gold quality
coronary artery	UBERON:0001621	92.48	gold quality
popliteal artery	UBERON:0002250	91.69	gold quality
tibial artery	UBERON:0007610	91.68	gold quality
upper lobe of left lung	UBERON:0008952	90.36	gold quality
metanephros cortex	UBERON:0010533	90.29	gold quality
seminal vesicle	UBERON:0000998	90.26	gold quality
apex of heart	UBERON:0002098	90.09	gold quality
aorta	UBERON:0000947	89.92	gold quality
body of uterus	UBERON:0009853	89.15	gold quality
tibial nerve	UBERON:0001323	88.83	gold quality
upper lobe of lung	UBERON:0008948	88.81	gold quality
descending thoracic aorta	UBERON:0002345	88.33	gold quality
ascending aorta	UBERON:0001496	88.14	gold quality
lower esophagus muscularis layer	UBERON:0035833	88.09	gold quality
lower esophagus	UBERON:0013473	88.06	gold quality
thoracic aorta	UBERON:0001515	87.94	gold quality
endocervix	UBERON:0000458	87.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.55	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	86.55	gold quality
adult mammalian kidney	UBERON:0000082	85.09	gold quality
caput epididymis	UBERON:0004358	84.39	gold quality
cortex of kidney	UBERON:0001225	84.16	gold quality
omental fat pad	UBERON:0010414	84.07	gold quality
sural nerve	UBERON:0015488	84.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	14.30

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.