TBX3-AS1

Summary

TBX3-AS1 (TBX3 antisense RNA 1, HGNC:55471) is a long non-coding RNA gene on chromosome 12q24.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55471
Approved symbol	TBX3-AS1
Name	TBX3 antisense RNA 1
Location	12q24.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000257817
Ensembl biotype	lncRNA
Entrez	105370000
RNAcentral	URS0000EF4151 — lncRNA, 1048 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 52 — 52 lncRNA

ENST00000551875, ENST00000653540, ENST00000660721, ENST00000662786, ENST00000667467, ENST00000669628, ENST00000671588, ENST00000839282, ENST00000839283, ENST00000839284, ENST00000839285, ENST00000839286, ENST00000839287, ENST00000839288, ENST00000839289, ENST00000839290, ENST00000839291, ENST00000839292, ENST00000839293, ENST00000839294, ENST00000839295, ENST00000839296, ENST00000839297, ENST00000839298, ENST00000839299, ENST00000839300, ENST00000839301, ENST00000839302, ENST00000839303, ENST00000839304, ENST00000839305, ENST00000839306, ENST00000839307, ENST00000839308, ENST00000839309, ENST00000839310, ENST00000839311, ENST00000839312, ENST00000839313, ENST00000839314, ENST00000839315, ENST00000839316, ENST00000839317, ENST00000839318, ENST00000839319, ENST00000839320, ENST00000839321, ENST00000839322, ENST00000839323, ENST00000839324, ENST00000839325, ENST00000839326

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000551875 — 5 exons

Exon	Start	End
ENSE00002333261	114767284	114767957
ENSE00002364439	114725652	114725746
ENSE00002365231	114713811	114713999
ENSE00002392506	114725277	114725533
ENSE00002394820	114748096	114748210

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 75.55.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	75.55	gold quality
right adrenal gland cortex	UBERON:0035827	70.74	gold quality
adrenal gland	UBERON:0002369	69.82	gold quality
left adrenal gland cortex	UBERON:0035825	68.97	gold quality
left adrenal gland	UBERON:0001234	68.69	gold quality
right adrenal gland	UBERON:0001233	68.33	gold quality
prostate gland	UBERON:0002367	67.71	gold quality
liver	UBERON:0002107	66.17	gold quality
right lobe of liver	UBERON:0001114	65.56	gold quality
ventricular zone	UBERON:0003053	59.94	gold quality
metanephros cortex	UBERON:0010533	59.73	gold quality
stromal cell of endometrium	CL:0002255	59.08	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.97	gold quality
calcaneal tendon	UBERON:0003701	58.38	gold quality
urinary bladder	UBERON:0001255	57.07	gold quality
muscle tissue	UBERON:0002385	56.19	gold quality
skeletal muscle tissue	UBERON:0001134	55.68	gold quality
thyroid gland	UBERON:0002046	55.50	gold quality
left lobe of thyroid gland	UBERON:0001120	55.23	gold quality
right lobe of thyroid gland	UBERON:0001119	54.23	gold quality
cortex of kidney	UBERON:0001225	53.57	gold quality
uterine cervix	UBERON:0000002	53.27	gold quality
left ovary	UBERON:0002119	52.78	gold quality
placenta	UBERON:0001987	52.67	gold quality
thoracic mammary gland	UBERON:0005200	52.64	gold quality
ovary	UBERON:0000992	52.10	gold quality
endocervix	UBERON:0000458	51.98	gold quality
lung	UBERON:0002048	51.98	gold quality
duodenum	UBERON:0002114	51.45	gold quality
vagina	UBERON:0000996	51.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.