TCF4-AS1

Summary

TCF4-AS1 (TCF4 antisense RNA 1, HGNC:51642) is a long non-coding RNA gene on chromosome 18q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51642
Approved symbol	TCF4-AS1
Name	TCF4 antisense RNA 1
Location	18q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	MIR4529HG
Ensembl gene	ENSG00000267028
Ensembl biotype	lncRNA
Entrez	105372127
RNAcentral	URS00008E3A6A — lncRNA, 411 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000587660

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000587660 — 2 exons

Exon	Start	End
ENSE00002779438	55452533	55452710
ENSE00002916528	55482723	55482940

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 85.10.

Top tissues by expression

210 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.10	silver quality
sural nerve	UBERON:0015488	84.51	gold quality
bone marrow cell	CL:0002092	70.44	silver quality
tendon of biceps brachii	UBERON:0008188	66.25	silver quality
calcaneal tendon	UBERON:0003701	63.76	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.74	gold quality
corpus callosum	UBERON:0002336	61.49	gold quality
adrenal tissue	UBERON:0018303	60.47	gold quality
tendon	UBERON:0000043	59.56	gold quality
islet of Langerhans	UBERON:0000006	58.43	gold quality
gall bladder	UBERON:0002110	56.82	gold quality
right uterine tube	UBERON:0001302	55.48	gold quality
gastrocnemius	UBERON:0001388	51.46	gold quality
monocyte	CL:0000576	51.37	silver quality
ectocervix	UBERON:0012249	50.87	gold quality
stomach	UBERON:0000945	50.42	gold quality
tibial artery	UBERON:0007610	50.36	gold quality
popliteal artery	UBERON:0002250	50.16	gold quality
adrenal gland	UBERON:0002369	50.01	gold quality
pancreas	UBERON:0001264	50.00	gold quality
endocervix	UBERON:0000458	49.75	gold quality
uterine cervix	UBERON:0000002	49.22	gold quality
adult mammalian kidney	UBERON:0000082	49.04	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.98	gold quality
nasal cavity mucosa	UBERON:0001826	48.72	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	48.60	gold quality
left coronary artery	UBERON:0001626	48.57	gold quality
prefrontal cortex	UBERON:0000451	48.41	gold quality
aorta	UBERON:0000947	48.18	gold quality
cerebellar cortex	UBERON:0002129	48.03	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.