TDH-AS1

Summary

TDH-AS1 (TDH antisense RNA 1, HGNC:55510) is a long non-coding RNA gene on chromosome 8p23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55510
Approved symbol	TDH-AS1
Name	TDH antisense RNA 1
Location	8p23.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AF131216.3
Ensembl gene	ENSG00000255020
Ensembl biotype	lncRNA
Entrez	100129129
RNAcentral	URS0000BC4648 — lncRNA, 1113 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000525867, ENST00000725209

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525867 — 2 exons

Exon	Start	End
ENSE00002150542	11345748	11346640
ENSE00004048580	11347297	11347538

Expression profiles

Bgee: expression breadth ubiquitous, 200 present calls, max score 94.65.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7716 / max 59.7410, expressed in 278 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
91831	0.7716	278

Top tissues by expression

215 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of paranasal sinus	UBERON:0005030	94.65	silver quality
superficial temporal artery	UBERON:0001614	93.20	silver quality
medial globus pallidus	UBERON:0002477	89.78	silver quality
sperm	CL:0000019	89.50	silver quality
substantia nigra pars reticulata	UBERON:0001966	89.41	gold quality
globus pallidus	UBERON:0001875	89.29	silver quality
secondary oocyte	CL:0000655	88.75	gold quality
epithelium of nasopharynx	UBERON:0001951	88.71	silver quality
lateral globus pallidus	UBERON:0002476	88.60	gold quality
vena cava	UBERON:0004087	88.32	gold quality
cardia of stomach	UBERON:0001162	88.03	silver quality
ventral tegmental area	UBERON:0002691	87.77	gold quality
buccal mucosa cell	CL:0002336	87.27	gold quality
lower lobe of lung	UBERON:0008949	87.10	silver quality
subthalamic nucleus	UBERON:0001906	86.93	gold quality
medulla oblongata	UBERON:0001896	85.95	gold quality
dorsal root ganglion	UBERON:0000044	85.93	gold quality
inferior vagus X ganglion	UBERON:0005363	85.82	gold quality
dorsal plus ventral thalamus	UBERON:0001897	85.57	gold quality
Brodmann (1909) area 23	UBERON:0013554	85.40	silver quality
superior vestibular nucleus	UBERON:0007227	85.07	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.19	silver quality
body of pancreas	UBERON:0001150	84.14	gold quality
substantia nigra pars compacta	UBERON:0001965	83.60	gold quality
superior surface of tongue	UBERON:0007371	83.47	silver quality
tongue	UBERON:0001723	83.38	silver quality
middle temporal gyrus	UBERON:0002771	83.06	silver quality
pons	UBERON:0000988	83.02	gold quality
cerebellar vermis	UBERON:0004720	82.65	silver quality
trachea	UBERON:0003126	82.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.70

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.