TENM2-AS1

Summary

TENM2-AS1 (TENM2 antisense RNA 1, HGNC:56066) is a long non-coding RNA gene on chromosome 5q34.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56066
Approved symbol	TENM2-AS1
Name	TENM2 antisense RNA 1
Location	5q34
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253978
Ensembl biotype	lncRNA
Entrez	101927862
RNAcentral	URS000075B590 — lncRNA, 518 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000519795, ENST00000655017, ENST00000794954, ENST00000794955, ENST00000794956, ENST00000794957, ENST00000794958, ENST00000794959, ENST00000794960, ENST00000794961, ENST00000794962, ENST00000794963, ENST00000794964, ENST00000794965, ENST00000794966, ENST00000794967, ENST00000794968

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000519795 — 4 exons

Exon	Start	End
ENSE00002127426	168230886	168231056
ENSE00004179245	168229580	168229860
ENSE00004179256	168232304	168232372
ENSE00004179268	168269274	168269470

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 87.48.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.48	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.40	gold quality
sural nerve	UBERON:0015488	80.79	gold quality
ventricular zone	UBERON:0003053	77.42	gold quality
adult mammalian kidney	UBERON:0000082	74.44	gold quality
endometrium	UBERON:0001295	72.82	gold quality
kidney	UBERON:0002113	71.42	gold quality
ganglionic eminence	UBERON:0004023	69.99	gold quality
metanephros cortex	UBERON:0010533	69.30	gold quality
cortex of kidney	UBERON:0001225	68.84	gold quality
substantia nigra	UBERON:0002038	68.81	gold quality
cortical plate	UBERON:0005343	68.08	gold quality
nucleus accumbens	UBERON:0001882	67.71	gold quality
amygdala	UBERON:0001876	67.60	gold quality
hypothalamus	UBERON:0001898	67.55	gold quality
temporal lobe	UBERON:0001871	67.49	gold quality
right atrium auricular region	UBERON:0006631	66.93	gold quality
putamen	UBERON:0001874	66.68	gold quality
heart left ventricle	UBERON:0002084	66.44	gold quality
caudate nucleus	UBERON:0001873	66.41	gold quality
heart	UBERON:0000948	65.69	gold quality
prostate gland	UBERON:0002367	65.39	gold quality
anterior cingulate cortex	UBERON:0009835	65.03	gold quality
Ammon’s horn	UBERON:0001954	64.02	gold quality
adenohypophysis	UBERON:0002196	63.91	gold quality
prefrontal cortex	UBERON:0000451	63.72	gold quality
brain	UBERON:0000955	63.43	gold quality
apex of heart	UBERON:0002098	63.28	gold quality
pituitary gland	UBERON:0000007	62.88	gold quality
cerebral cortex	UBERON:0000956	62.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.