TENM3-AS1

Summary

TENM3-AS1 (TENM3 antisense RNA 1, HGNC:28076) is a long non-coding RNA gene on chromosome 4q34.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28076
Approved symbol	TENM3-AS1
Name	TENM3 antisense RNA 1
Location	4q34.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000177822
Ensembl biotype	lncRNA
Entrez	90768
RNAcentral	URS00007E3D16 — lncRNA, 3353 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 58 — 58 lncRNA

ENST00000315302, ENST00000505537, ENST00000505873, ENST00000507869, ENST00000508968, ENST00000509012, ENST00000510211, ENST00000511052, ENST00000513752, ENST00000669431, ENST00000702033, ENST00000715797, ENST00000763496, ENST00000763497, ENST00000763498, ENST00000763499, ENST00000763500, ENST00000763501, ENST00000763502, ENST00000763503, ENST00000763504, ENST00000763505, ENST00000763506, ENST00000763507, ENST00000763508, ENST00000763509, ENST00000763510, ENST00000763511, ENST00000763512, ENST00000763513, ENST00000763514, ENST00000763515, ENST00000763516, ENST00000763517, ENST00000763518, ENST00000763519, ENST00000763520, ENST00000763521, ENST00000763522, ENST00000763523, ENST00000763524, ENST00000763525, ENST00000763526, ENST00000763527, ENST00000763528, ENST00000763529, ENST00000763530, ENST00000763531, ENST00000763532, ENST00000763533, ENST00000763534, ENST00000763535, ENST00000763536, ENST00000763537, ENST00000763538, ENST00000763539, ENST00000763540, ENST00000763541

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000315302 — 4 exons

Exon	Start	End
ENSE00001234636	182143703	182143844
ENSE00004119696	182144047	182144140
ENSE00004119730	182141640	182143545
ENSE00004119745	182144339	182144557

Expression profiles

Bgee: expression breadth ubiquitous, 148 present calls, max score 90.98.

FANTOM5 (CAGE): breadth broad, TPM avg 2.6266 / max 51.7560, expressed in 884 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55075	1.0254	529
55077	0.7640	460
55074	0.4091	142
55076	0.3096	183
55073	0.0819	49
55072	0.0365	23

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreatic ductal cell	CL:0002079	90.98	silver quality
sural nerve	UBERON:0015488	83.84	gold quality
adrenal tissue	UBERON:0018303	81.56	gold quality
colonic epithelium	UBERON:0000397	78.78	gold quality
stromal cell of endometrium	CL:0002255	75.00	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	71.12	gold quality
omental fat pad	UBERON:0010414	71.08	gold quality
peritoneum	UBERON:0002358	71.00	gold quality
adipose tissue of abdominal region	UBERON:0007808	69.72	gold quality
tibialis anterior	UBERON:0001385	68.97	silver quality
ileal mucosa	UBERON:0000331	68.42	silver quality
adenohypophysis	UBERON:0002196	67.17	gold quality
left adrenal gland	UBERON:0001234	66.35	gold quality
left adrenal gland cortex	UBERON:0035825	66.34	gold quality
adrenal gland	UBERON:0002369	66.00	gold quality
tibial nerve	UBERON:0001323	65.88	gold quality
right adrenal gland	UBERON:0001233	65.81	gold quality
subcutaneous adipose tissue	UBERON:0002190	65.62	gold quality
cortical plate	UBERON:0005343	64.38	gold quality
adrenal cortex	UBERON:0001235	63.85	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.59	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.14	gold quality
pituitary gland	UBERON:0000007	62.99	gold quality
right adrenal gland cortex	UBERON:0035827	62.89	gold quality
left lobe of thyroid gland	UBERON:0001120	62.83	gold quality
adipose tissue	UBERON:0001013	62.66	gold quality
descending thoracic aorta	UBERON:0002345	62.31	gold quality
thyroid gland	UBERON:0002046	62.14	gold quality
nucleus accumbens	UBERON:0001882	61.69	gold quality
prefrontal cortex	UBERON:0000451	61.23	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.39

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.