TEPSIN-AS1

Summary

TEPSIN-AS1 (TEPSIN antisense RNA 1, HGNC:58197) is a long non-coding RNA gene on chromosome 17q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58197
Approved symbol	TEPSIN-AS1
Name	TEPSIN antisense RNA 1
Location	17q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260005
Ensembl biotype	lncRNA
Entrez	105371925
RNAcentral	URS0000A774BB — lncRNA, 1452 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000569559, ENST00000575922

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000569559 — 4 exons

Exon	Start	End
ENSE00002578482	81229341	81229377
ENSE00002591576	81231858	81232206
ENSE00002613206	81229738	81229927
ENSE00002622278	81230002	81230240

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 77.62.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.62	silver quality
granulocyte	CL:0000094	75.30	gold quality
sural nerve	UBERON:0015488	72.98	gold quality
spleen	UBERON:0002106	72.30	gold quality
blood	UBERON:0000178	71.11	gold quality
bone marrow	UBERON:0002371	70.53	gold quality
mucosa of transverse colon	UBERON:0004991	70.04	gold quality
apex of heart	UBERON:0002098	69.07	gold quality
small intestine Peyer’s patch	UBERON:0003454	67.80	gold quality
lower esophagus mucosa	UBERON:0035834	67.74	gold quality
bone marrow cell	CL:0002092	67.68	silver quality
small intestine	UBERON:0002108	67.11	gold quality
lymph node	UBERON:0000029	66.64	gold quality
right lobe of liver	UBERON:0001114	66.43	gold quality
stromal cell of endometrium	CL:0002255	66.16	gold quality
metanephros cortex	UBERON:0010533	64.99	gold quality
body of stomach	UBERON:0001161	64.88	gold quality
vermiform appendix	UBERON:0001154	64.68	gold quality
transverse colon	UBERON:0001157	64.55	gold quality
esophagus mucosa	UBERON:0002469	64.29	gold quality
right adrenal gland cortex	UBERON:0035827	64.01	gold quality
stomach	UBERON:0000945	63.96	gold quality
right adrenal gland	UBERON:0001233	63.90	gold quality
right lobe of thyroid gland	UBERON:0001119	63.83	gold quality
intestine	UBERON:0000160	63.70	gold quality
liver	UBERON:0002107	63.51	gold quality
left adrenal gland cortex	UBERON:0035825	63.45	gold quality
esophagus	UBERON:0001043	63.38	gold quality
monocyte	CL:0000576	63.31	gold quality
left adrenal gland	UBERON:0001234	63.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.