TERT-AS1

Summary

TERT-AS1 (TERT antisense RNA 1, HGNC:58990) is a long non-coding RNA gene on chromosome 5p15.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58990
Approved symbol	TERT-AS1
Name	TERT antisense RNA 1
Location	5p15.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000287486
Ensembl biotype	lncRNA
Entrez	144667545

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000666708

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000666708 — 3 exons

Exon	Start	End
ENSE00003856921	1254674	1254733
ENSE00003869117	1252006	1252293
ENSE00003876380	1255306	1255976

Expression profiles

Bgee: expression breadth broad, 39 present calls, max score 77.81.

Top tissues by expression

39 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
duodenum	UBERON:0002114	77.81	gold quality
small intestine	UBERON:0002108	64.70	gold quality
small intestine Peyer’s patch	UBERON:0003454	64.02	gold quality
stromal cell of endometrium	CL:0002255	61.11	gold quality
intestine	UBERON:0000160	57.31	gold quality
ovary	UBERON:0000992	55.90	gold quality
liver	UBERON:0002107	55.86	gold quality
mucosa of transverse colon	UBERON:0004991	53.94	gold quality
lower esophagus muscularis layer	UBERON:0035833	53.90	gold quality
vermiform appendix	UBERON:0001154	53.34	gold quality
colon	UBERON:0001155	51.26	gold quality
transverse colon	UBERON:0001157	51.07	gold quality
multicellular organism	UBERON:0000468	49.45	gold quality
gastrocnemius	UBERON:0001388	49.33	gold quality
blood	UBERON:0000178	48.91	silver quality
kidney	UBERON:0002113	48.73	silver quality
lymph node	UBERON:0000029	47.44	silver quality
tonsil	UBERON:0002372	45.26	gold quality
muscle layer of sigmoid colon	UBERON:0035805	45.03	gold quality
prefrontal cortex	UBERON:0000451	44.64	silver quality
tibial artery	UBERON:0007610	43.79	silver quality
rectum	UBERON:0001052	42.46	silver quality
skin of leg	UBERON:0001511	41.84	silver quality
spleen	UBERON:0002106	41.73	silver quality
esophagus mucosa	UBERON:0002469	41.28	silver quality
stomach	UBERON:0000945	41.08	silver quality
nucleus accumbens	UBERON:0001882	39.74	silver quality
substantia nigra	UBERON:0002038	39.17	silver quality
putamen	UBERON:0001874	38.70	silver quality
body of stomach	UBERON:0001161	38.06	silver quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.