TESHL

Summary

TESHL (testicular germ cell expressed HSF2 interacting lncRNA, HGNC:52740) is a long non-coding RNA gene on chromosome 2q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52740
Approved symbol	TESHL
Name	testicular germ cell expressed HSF2 interacting lncRNA
Location	2q35
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223874
Ensembl biotype	lncRNA
Entrez	101928327
RNAcentral	URS000081211A — lncRNA, 413 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 72 — 72 lncRNA

ENST00000447289, ENST00000451711, ENST00000452813, ENST00000456163, ENST00000607591, ENST00000655995, ENST00000656038, ENST00000657418, ENST00000657920, ENST00000666026, ENST00000666326, ENST00000695932, ENST00000695933, ENST00000695934, ENST00000695935, ENST00000695936, ENST00000695937, ENST00000695938, ENST00000695939, ENST00000695940, ENST00000695941, ENST00000702642, ENST00000715604, ENST00000715605, ENST00000745093, ENST00000745094, ENST00000745095, ENST00000745096, ENST00000745097, ENST00000745098, ENST00000745099, ENST00000745100, ENST00000745101, ENST00000772330, ENST00000772331, ENST00000772332, ENST00000772333, ENST00000772334, ENST00000772335, ENST00000772336, ENST00000772337, ENST00000838352, ENST00000838353, ENST00000838354, ENST00000838355, ENST00000838356, ENST00000838357, ENST00000838358, ENST00000838359, ENST00000838360, ENST00000838361, ENST00000838362, ENST00000838363, ENST00000838364, ENST00000838365, ENST00000838366, ENST00000838367, ENST00000838368, ENST00000838369, ENST00000838370, ENST00000838371, ENST00000838372, ENST00000838373, ENST00000838374, ENST00000838375, ENST00000838376, ENST00000838377, ENST00000838378, ENST00000838379, ENST00000838380, ENST00000838381, ENST00000838382

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447289 — 4 exons

Exon	Start	End
ENSE00001618755	216993958	216993999
ENSE00001643953	216694464	216694761
ENSE00001729429	216764889	216765010
ENSE00003965530	216712380	216712469

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 99.78.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1582 / max 174.5699, expressed in 6 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
25251	0.1356	5
25260	0.0666	23
25249	0.0169	4
25248	0.0057	2
25259	0.0020	1

Top tissues by expression

209 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	99.78	gold quality
left testis	UBERON:0004533	98.37	gold quality
right testis	UBERON:0004534	97.54	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.85	gold quality
testis	UBERON:0000473	96.07	gold quality
adult organism	UBERON:0007023	92.48	gold quality
pancreatic ductal cell	CL:0002079	76.29	silver quality
buccal mucosa cell	CL:0002336	68.61	gold quality
calcaneal tendon	UBERON:0003701	64.85	gold quality
sural nerve	UBERON:0015488	63.64	silver quality
tibialis anterior	UBERON:0001385	63.32	silver quality
ileal mucosa	UBERON:0000331	62.07	silver quality
hindlimb stylopod muscle	UBERON:0004252	60.43	gold quality
tendon	UBERON:0000043	58.49	silver quality
tendon of biceps brachii	UBERON:0008188	56.85	gold quality
epithelial cell of pancreas	CL:0000083	56.63	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.93	gold quality
upper lobe of lung	UBERON:0008948	54.69	silver quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
monocyte	CL:0000576	54.07	silver quality
kidney epithelium	UBERON:0004819	53.93	gold quality
islet of Langerhans	UBERON:0000006	53.87	gold quality
cauda epididymis	UBERON:0004360	53.55	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
gastrocnemius	UBERON:0001388	51.75	gold quality
myocardium	UBERON:0002349	51.48	gold quality
skin of hip	UBERON:0001554	50.29	silver quality
metanephros cortex	UBERON:0010533	49.54	gold quality
right lobe of liver	UBERON:0001114	49.48	silver quality
tibial artery	UBERON:0007610	48.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.