TET2-AS1

Summary

TET2-AS1 (TET2 antisense RNA 1, HGNC:41125) is a long non-coding RNA gene on chromosome 4q24.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41125
Approved symbol	TET2-AS1
Name	TET2 antisense RNA 1
Location	4q24
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251586
Ensembl biotype	lncRNA
Entrez	104384744
RNAcentral	URS00007E443A — lncRNA, 754 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000515414, ENST00000776423, ENST00000776424, ENST00000776425, ENST00000776426, ENST00000776427, ENST00000776428

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000515414 — 5 exons

Exon	Start	End
ENSE00002020717	105172416	105172578
ENSE00002021872	105177592	105177672
ENSE00002038972	105171354	105171400
ENSE00002051122	105177963	105178063
ENSE00002067863	105171587	105171731

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 79.38.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1315 / max 13.0498, expressed in 68 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
53463	0.0767	43
53462	0.0548	41

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	79.38	gold quality
adrenal tissue	UBERON:0018303	74.00	gold quality
bone marrow	UBERON:0002371	73.22	gold quality
corpus callosum	UBERON:0002336	70.88	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.38	gold quality
monocyte	CL:0000576	67.82	gold quality
leukocyte	CL:0000738	67.71	gold quality
calcaneal tendon	UBERON:0003701	67.05	gold quality
skeletal muscle tissue	UBERON:0001134	65.30	gold quality
duodenum	UBERON:0002114	65.22	gold quality
blood	UBERON:0000178	64.08	gold quality
lower esophagus mucosa	UBERON:0035834	61.34	gold quality
muscle of leg	UBERON:0001383	61.22	gold quality
sural nerve	UBERON:0015488	60.77	gold quality
gastrocnemius	UBERON:0001388	60.51	gold quality
tonsil	UBERON:0002372	59.88	gold quality
popliteal artery	UBERON:0002250	58.22	gold quality
tibial artery	UBERON:0007610	58.15	gold quality
lower esophagus	UBERON:0013473	57.34	gold quality
lower esophagus muscularis layer	UBERON:0035833	57.26	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	56.20	gold quality
heart left ventricle	UBERON:0002084	55.90	gold quality
liver	UBERON:0002107	54.73	gold quality
placenta	UBERON:0001987	54.65	gold quality
heart	UBERON:0000948	54.44	gold quality
muscle layer of sigmoid colon	UBERON:0035805	54.00	gold quality
esophagus	UBERON:0001043	53.92	gold quality
descending thoracic aorta	UBERON:0002345	53.82	gold quality
vermiform appendix	UBERON:0001154	53.47	gold quality
prefrontal cortex	UBERON:0000451	53.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.