TFEB-AS1

Summary

TFEB-AS1 (TFEB antisense RNA 1, HGNC:40580) is a long non-coding RNA gene on chromosome 6p21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40580
Approved symbol	TFEB-AS1
Name	TFEB antisense RNA 1
Location	6p21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231102
Ensembl biotype	lncRNA
Entrez	141487635

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000438967

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438967 — 2 exons

Exon	Start	End
ENSE00001625691	41720396	41720688
ENSE00001772086	41733918	41734032

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 75.62.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	75.62	gold quality
corpus callosum	UBERON:0002336	72.26	gold quality
colonic epithelium	UBERON:0000397	71.37	gold quality
skeletal muscle tissue	UBERON:0001134	71.23	gold quality
bone marrow	UBERON:0002371	69.11	gold quality
blood	UBERON:0000178	68.32	gold quality
lymph node	UBERON:0000029	65.32	gold quality
monocyte	CL:0000576	64.23	gold quality
tonsil	UBERON:0002372	63.85	gold quality
cortex of kidney	UBERON:0001225	60.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.51	gold quality
liver	UBERON:0002107	59.53	gold quality
islet of Langerhans	UBERON:0000006	58.42	gold quality
calcaneal tendon	UBERON:0003701	56.89	gold quality
urinary bladder	UBERON:0001255	56.84	gold quality
prefrontal cortex	UBERON:0000451	56.83	gold quality
placenta	UBERON:0001987	55.84	gold quality
primary visual cortex	UBERON:0002436	55.61	gold quality
muscle of leg	UBERON:0001383	55.10	gold quality
kidney	UBERON:0002113	54.33	gold quality
gastrocnemius	UBERON:0001388	54.05	gold quality
pancreas	UBERON:0001264	52.86	gold quality
uterine cervix	UBERON:0000002	51.96	silver quality
myometrium	UBERON:0001296	51.92	gold quality
adrenal tissue	UBERON:0018303	51.61	gold quality
multicellular organism	UBERON:0000468	51.04	gold quality
heart left ventricle	UBERON:0002084	50.26	gold quality
body of pancreas	UBERON:0001150	49.28	gold quality
spleen	UBERON:0002106	49.02	gold quality
adrenal gland	UBERON:0002369	49.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.